Title : Mechanisms of acquired resistance of BRCA1/2-driven tumors to platinum compounds and PARP inhibitors.

Pub. Date : 2021 Jul 24

PMID : 34367927






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This platinum/PARPi cross-resistance mechanism applies both for BRCA1 and BRCA2 genes and has been repeatedly validated in various laboratory models and multiple clinical studies. Platinum BRCA2 DNA repair associated Homo sapiens