Title : Towards precision oncology in advanced prostate cancer.

Pub. Date : 2019 Nov

PMID : 31591549






1 Functional Relationships(s)
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1 The detection of DNA repair aberrations, such as mutation of BRCA2, could help select patients for poly(ADP-ribose) polymerase (PARP) inhibitor or platinum chemotherapy, and mismatch repair gene defects and microsatellite instability have been associated with responses to checkpoint inhibitor immunotherapy. Platinum BRCA2 DNA repair associated Homo sapiens