Fluorouracil

thymidine phosphorylase ; Homo sapiens







79 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34843983 Vesicular IFN-γ as a cooperative attacker to enhance anti-cancer effect of 5-fluorouracil via thymidine phosphorylase upregulation and tumor microenvironment normalization. 2022 Feb 4
2 35093881 Effect of Thymidine Phosphorylase Gene Demethylation on Sensitivity to 5-Fluorouracil in Colorectal Cancer Cells. 2022 Feb 8
3 35193822 Multifunctional role of thymidine phosphorylase in cancer. 2022 Jun 4
4 33276189 Fluorescent molecular rotors as sensors for the detection of thymidine phosphorylase. 2021 Jan 1 1
5 33731881 Mucinous and non-mucinous colorectal cancers show differential expression of chemotherapy metabolism and resistance genes. 2021 Aug 1
6 33874986 Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5'-deoxy-5-fluorocytidine (5'-DFCR). 2021 Apr 19 1
7 34299320 Enhanced Vasculogenic Capacity Induced by 5-Fluorouracil Chemoresistance in a Gastric Cancer Cell Line. 2021 Jul 19 2
8 32005747 Predictive Biomarkers for Adjuvant Capecitabine Benefit in Early-Stage Triple-Negative Breast Cancer in the FinXX Clinical Trial. 2020 Jun 1 1
9 32066801 5-Nitrouracil stabilizes the plasma concentration values of 5-FU in colorectal cancer patients receiving capecitabine. 2020 Feb 17 4
10 30649964 Capecitabine for the treatment of pancreatic cancer. 2019 Mar 7
11 30728402 FOXM1 modulates 5-FU resistance in colorectal cancer through regulating TYMS expression. 2019 Feb 6 1
12 29701074 Thymidine phosphorylase: the unforeseen driver in colorectal cancer treatment? 2018 May 2
13 30285552 Development and validation of a quantitative method for thymidine phosphorylase activity in peripheral blood mononuclear cells. 2018 2
14 28127745 5-fluorouracil causes endothelial cell senescence: potential protective role of glucagon-like peptide 1. 2017 Nov 1
15 27569869 The role of pharmacogenetics in capecitabine efficacy and toxicity. 2016 Nov 1
16 25877313 [Transfection of thymidine phosphorylase cDNA with lentiviral vector enhances the anticancer effect of 5'-deoxy-5-fluorouridine on colorectal cancer cell lines HT29 and LS174T]. 2015 Jan 12
17 26623038 Superior antitumor activity of trastuzumab combined with capecitabine plus oxaliplatin in a human epidermal growth factor receptor 2-positive human gastric cancer xenograft model. 2015 Sep 2
18 24936150 Thymidine phosphorylase expression is associated with time to progression in patients with metastatic colorectal cancer. 2014 2
19 25364408 Thymidine phosphorylase mRNA expression may be a predictor of response to post-operative adjuvant chemotherapy with S-1 in patients with stage III colorectal cancer. 2014 Dec 3
20 25537222 The influence of 5-fluorouracil on activity of thymidine phosphorylase in gastric adenocarcinoma and normal adjacent tissue. 2014 Dec 8
21 23608802 [Effect of thymidine phosphorylase cDNA transfection on the inhibition of human colon carcinoma cell line by 5'-deoxy-5-fluorouridine]. 2013 Apr 2
22 23861589 Clinical significance of the thymidylate synthase, dihydropyrimidine dehydrogenase, and thymidine phosphorylase mRNA expressions in hepatocellular carcinoma patients receiving 5-fluorouracil-based transarterial chemoembolization treatment. 2013 5
23 23160694 Predictive role of thymidine phosphorylase expression in patients with colorectal cancer and its association with angiogenesis-related proteins and extracellular matrix components. 2012 Nov-Dec 4
24 21444628 Up-regulation of extracellular signal-regulated kinase 1/2-dependent thymidylate synthase and thymidine phosphorylase contributes to cisplatin resistance in human non-small-cell lung cancer cells. 2011 Jul 2
25 21756828 [Improved sensitivity of gastric carcinoma cells to fluorouracil-related drugs by transfection of thymidine phosphorylase gene]. 2011 May 5
26 21791367 Thymidylate synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, orotate phosphoribosyltransferase mRNA expression in lung cancer metastatic lymph node samples obtained by endobronchial ultrasound-guided transbronchial needle aspiration: a pilot study. 2011 Sep 4
27 20355241 Effects of thymidine phosphorylase on tumor aggressiveness and 5-fluorouracil sensitivity in cholangiocarcinoma. 2010 Apr 7 2
28 20837458 Low thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase mRNA expression correlate with prolonged survival in resected non-small-cell lung cancer. 2010 Sep 1 2
29 22966291 High expression of thymidine phosphorylase in basal-like breast cancers: Stromal expression in EGFR- and/or CK5/6-positive breast cancers. 2010 Mar 2
30 19015148 Comparison of 5-fluorouracil-related gene expression levels between adenocarcinomas and squamous cell carcinomas of the lung. 2009 Jan 1
31 17364369 Thymidine phosphorylase mRNA level predicts survival of patients with advanced oropharyngeal cancer. 2007 Mar 4
32 17443278 Role of thymidine phosphorylase and orotate phosphoribosyltransferase mRNA expression and its ratio to dihydropyrimidine dehydrogenase in the prognosis and clinicopathological features of patients with pancreatic cancer. 2007 Apr 1
33 16552801 Apoptosis induced by preoperative oral 5'-DFUR administration in gastric adenocarcinoma and its mechanism of action. 2006 Mar 7 1
34 16872266 Capecitabine in carcinoma of the pancreas. 2006 Aug 1
35 17179731 Predictive role of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer patients receiving adjuvant 5-fluorouracil. 2006 2
36 18221035 Thymidine phosphorylase (platelet-derived endothelial cell growth factor) as a target for capecitabine: from biology to the bedside. 2006 Jun 4
37 15655543 Unfavourable expression of pharmacologic markers in mucinous colorectal cancer. 2005 Jan 31 1
38 15890242 Thymidylate synthase and dihydropyrimidine dehydrogenase gene expression in breast cancer predicts 5-FU sensitivity by a histocultural drug sensitivity test. 2005 Jun 1 4
39 15999119 Expression of thymidylate synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, and orotate phosphoribosyl transferase in prostate cancer. 2005 1
40 16160472 Immunohistochemical analysis of thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase in rectal cancer (cUICC II/III): correlation with histopathologic tumor regression after 5-fluorouracil-based long-term neoadjuvant chemoradiotherapy. 2005 Oct 1
41 19956517 Thymidylate synthase, thymidine phosphorylase, VEGF and p53 protein expression in primary colorectal cancer for predicting response to 5-fluorouracil-based chemotherapy. 2005 Aug 2
42 14614573 Thymidine phosphorylase expression is preserved after radiotherapy in patients with cervical squamous cell carcinoma. 2004 Feb 2
43 15150550 Modulation of thymidine phosphorylase by neoadjuvant chemotherapy in primary breast cancer. 2004 Jun 14 5
44 15301717 [Enhancement effect of interferon gamma on the sensitivity of RT4 bladder cancer cells to 5'-deoxy-5-fluorouridine,and 5-fluorouracil through up-regulation of PD-ECGF/TP]. 2004 Aug 4
45 15604581 Comparative antitumor activity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in combination with interferon-alpha in renal cell carcinoma cell lines. 2004 6
46 12497203 Clinical significance of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in transitional cell cancer. 2003 Jan 3
47 12507543 Thymidine phosphorylase and dihydropyrimidine dehydrogenase in renal cell carcinoma: relationship between histological parameters and chemosensitivity to 5-fluorouracil. 2003 Jan 6
48 12016389 Thymidine phosphorylase is regulated by tamoxifen in T47D breast cancer cell line. 2002 4
49 12019408 Prognostic value of thymidine phosphorylase/platelet-derived endothelial cell growth factor in advanced colorectal cancer after surgery: evaluation with a new monoclonal antibody. 2002 May 2
50 12020396 Prognostic and predictive value of thymidine phosphorylase activity in early-stage breast cancer patients. 2002 Apr 2