Fluorouracil

thymidine phosphorylase ; Homo sapiens







79 Article(s)
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51 12529971 IFN gamma-induced up-regulation of PD-ECGF/TP enhances the cytotoxicity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in bladder cancer cells. 2002 Sep-Oct 1
52 12552961 The rational development of capecitabine from the laboratory to the clinic. 2002 Nov-Dec 1
53 12553027 Comparative antitumor activity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in combination with interferon gamma in renal cell carcinoma cell lines. 2002 Nov-Dec 6
54 11391857 Heterogeneic distribution of thymidine phosphorylase between primary tumors and metastatic lesions of human pancreatic ductal carcinoma: implications for the efficacy of chemotherapy with 5-FU or its derivatives. 2001 May 1
55 11562746 Thymidine phosphorylase expression is useful in selecting adjuvant chemotherapy for stage III gastric cancer. 2001 Oct 6
56 12467230 Combination of thymidine phosphorylase gene transfer and deoxyinosine treatment greatly enhances 5-fluorouracil antitumor activity in vitro and in vivo. 2001 Dec 9
57 10778957 Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. 2000 Apr 1
58 11073333 Platelet-derived endothelial cell growth factor expression and angiogenesis in cervical intraepithelial neoplasia and squamous cell carcinoma of the cervix. 2000 Oct 1
59 11205264 Thymidine phosphorylase activity in transitional cell cancer: relation to histological parameters and chemosensitivity to fluorouracil-related drugs. 2000 Nov-Dec 2
60 10412941 Biomodulation of 5-fluorouracil by interferon-alpha in human renal carcinoma cells: relationship to the expression of thymidine phosphorylase. 1999 5
61 10468288 Increased cytotoxicity and bystander effect of 5-fluorouracil and 5-deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase. 1999 Aug 8
62 10507774 The expression of thymidine phosphorylase correlates with angiogenesis and the efficacy of chemotherapy using fluorouracil derivatives in advanced gastric carcinoma. 1999 Oct 2
63 10530779 Augmentation of antitumor activity of 5'-deoxy-5-fluorouridine by thymosin fraction 5 in mouse bladder cancer cells in vitro and in vivo. 1999 Oct 18 2
64 10697613 Thymidine phosphorylase expression in invasive carcinoma: correlations with clinicopathologic variables and in vitro chemosensitivity to 5-fluorouracil. 1999 Nov-Dec 4
65 10766293 The rĂ´le of thymidine phosphorylase/PD-ECGF in cancer chemotherapy: a chemical perspective. 1999 Oct 1
66 11504493 Thymidine phosphorylase: its role in sensitivity and resistance to anticancer drugs. 1999 Aug 1
67 9524089 In vitro study on intrathecal use of 5-fluoro-2'-deoxyuridine (FdUrd) for meningeal dissemination of malignant brain tumors. 1998 Apr 1
68 9537263 Regulation of expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor in human colon carcinoma cells. 1998 Apr 1 1
69 9676830 Expression of platelet-derived endothelial cell growth factor in oral and oropharyngeal carcinoma. 1998 Jul 3
70 9757455 [In vitro study on intrathecal application of 5-fluoro-2'-deoxyuridine (FdUrd) for meningeal dissemination of malignant tumor]. 1998 Sep 1
71 9796967 High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil. 1998 Oct 9
72 9797804 [Cancer-associated gene abnormalities and chemosensitivity]. 1998 Oct 1
73 9310231 Platelet-derived endothelial cell growth factor thymidine phosphorylase in tumour growth and response to therapy. 1997 1
74 9815767 Interferon induces thymidine phosphorylase/platelet-derived endothelial cell growth factor expression in vivo. 1997 Jun 2
75 21590142 The influence of pyrimidine nucleoside phosphorylase activity on metastasis of breast cancer. 1997 Jul-Aug 1
76 7627962 5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression. 1995 Aug 15 6
77 7642571 Thymidine phosphorylase mediates the sensitivity of human colon carcinoma cells to 5-fluorouracil. 1995 Aug 11 2
78 8137250 Potentiation of the antitumor activity of 5-fluorouracil in colon carcinoma cells by the combination of interferon and deoxyribonucleosides results from complementary effects on thymidine phosphorylase. 1994 Mar 15 1
79 8339382 Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5'-deoxy-5-fluorouridine. 1993 1