Title : Thymidine phosphorylase mRNA expression may be a predictor of response to post-operative adjuvant chemotherapy with S-1 in patients with stage III colorectal cancer.

Pub. Date : 2014 Dec

PMID : 25364408






3 Functional Relationships(s)
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Protein Name
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1 The 5-FU metabolizing enzymes studied were thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase (TP). Fluorouracil thymidine phosphorylase Homo sapiens
2 The 5-FU metabolizing enzymes studied were thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase (TP). Fluorouracil thymidine phosphorylase Homo sapiens
3 These results indicate that the mRNA expression of TP, a metabolizing enzyme of 5-FU, is a significant predictor of response to post-operative chemotherapy with S-1 in patients with stage III colorectal cancer. Fluorouracil thymidine phosphorylase Homo sapiens