Pub. Date : 2022 Feb
PMID : 34843983
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Vesicular IFN-gamma as a cooperative attacker to enhance anti-cancer effect of 5-fluorouracil via thymidine phosphorylase upregulation and tumor microenvironment normalization. | Fluorouracil | thymidine phosphorylase | Homo sapiens |
| 2 | On the basis of immuno-modulating effect and upregulating the activity of thymidine phosphorylase (TP), interferon-gamma (IFN-gamma) as a cooperative attacker was explored to enhance the anticancer activity of 5-FU. | Fluorouracil | thymidine phosphorylase | Homo sapiens |
| 3 | On the basis of immuno-modulating effect and upregulating the activity of thymidine phosphorylase (TP), interferon-gamma (IFN-gamma) as a cooperative attacker was explored to enhance the anticancer activity of 5-FU. | Fluorouracil | thymidine phosphorylase | Homo sapiens |
| 4 | The IFN-gamma-EDP vesicles allowed IFN-gamma to accumulate at the tumor site and be taken up by tumor cells, resulting in significantly upregulated expression level of TP, distinct inhibition of cell growth, more cellular apoptosis and more serious cell cycle arrest when administrated combined with 5-FU. | Fluorouracil | thymidine phosphorylase | Homo sapiens |