pegvisomant

insulin like growth factor 1 ; Homo sapiens







156 Article(s)
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51 20407837 Failure of temozolomide and conventional doses of pegvisomant to attain biochemical control in a severe case of acromegaly. 2012 Mar 3
52 22162472 Growth hormone receptor variants and response to pegvisomant in monotherapy or in combination with somatostatin analogs in acromegalic patients: a multicenter study. 2012 Feb 1
53 22278424 Effective combination treatment with cabergoline and low-dose pegvisomant in active acromegaly: a prospective clinical trial. 2012 Apr 3
54 22362824 Long-term safety of pegvisomant in patients with acromegaly: comprehensive review of 1288 subjects in ACROSTUDY. 2012 May 1
55 22408123 GH activity and markers of inflammation: a crossover study in healthy volunteers treated with GH and a GH receptor antagonist. 2012 May 1
56 23186966 Diabetic Ketoacidosis in Acromegaly: A Case Report. 2012 Nov 27 1
57 23930065 A case of an acromegalic patient resistant to the recommended maximum GH receptor antagonist dosage. 2012 Jan 1
58 21045065 Hypothesis: Extra-hepatic acromegaly: a new paradigm? 2011 Jan 2
59 21104581 Inhibition of growth hormone receptor activation by pegvisomant may increase bone density in acromegaly. 2011 Jan 1
60 21148630 Coadministration of lanreotide Autogel and pegvisomant normalizes IGF1 levels and is well tolerated in patients with acromegaly partially controlled by somatostatin analogs alone. 2011 Mar 3
61 21209237 Population pharmacokinetic and pharmacodynamic modeling of pegvisomant in asian and Western acromegaly patients. 2011 Dec 4
62 21221818 Conversion of daily pegvisomant to weekly pegvisomant combined with long-acting somatostatin analogs, in controlled acromegaly patients. 2011 Sep 3
63 21498100 GH receptor blocker administration and muscle-tendon collagen synthesis in humans. 2011 Jun 1
64 18498055 Endogenous estradiol may influence IGF-I levels in acromegalic women treated with pegvisomant. 2010 3
65 19850678 The exon 3-deleted growth hormone receptor is associated with better response to pegvisomant therapy in acromegaly. 2010 Jan 2
66 20050861 Change of symptoms and perceived health in acromegalic patients on pegvisomant therapy: a retrospective cohort study within the German Pegvisomant Observational Study (GPOS). 2010 Jul 2
67 20190543 Eight-year follow-up of a child with a GH/prolactin-secreting adenoma: efficacy of pegvisomant therapy. 2010 1
68 20887124 Pharmacological management of acromegaly: a current perspective. 2010 Oct 1
69 19018786 Long-term experience of pegvisomant therapy as a treatment for acromegaly. 2009 Jul 1
70 19067728 Use of a GH receptor antagonist (GHRA) to explore the relationship between GH and IGF-I in adults with severe GH deficiency (GHD). 2009 Mar 4
71 19141604 Combined treatment for acromegaly with long-acting somatostatin analogs and pegvisomant: long-term safety for up to 4.5 years (median 2.2 years) of follow-up in 86 patients. 2009 Apr 1
72 19147599 Long-term treatment of acromegalic patients resistant to somatostatin analogues with the GH receptor antagonist pegvisomant: its efficacy in relation to gender and previous radiotherapy. 2009 Apr 1
73 19153502 Pitfalls of insulin-like growth factor I assays. 2009 Jan 1
74 19258431 Pegvisomant-induced cholestatic hepatitis with jaundice in a patient with Gilbert's syndrome. 2009 May 1
75 19366854 Pegvisomant improves insulin sensitivity and reduces overnight free fatty acid concentrations in patients with acromegaly. 2009 Jul 2
76 19411301 Successful use of weekly pegvisomant administration in patients with acromegaly. 2009 Jul 3
77 19444656 Current therapy and drug pipeline for the treatment of patients with acromegaly. 2009 Apr 1
78 19684052 ACROSTUDY: the first 5 years. 2009 Nov 1
79 19684061 The German ACROSTUDY: past and present. 2009 Nov 1
80 19763127 Somatostatin analog and pegvisomant combination therapy for acromegaly. 2009 Oct 1
81 19814797 Clinical effectiveness and cost-effectiveness of pegvisomant for the treatment of acromegaly: a systematic review and economic evaluation. 2009 Oct 8 4
82 20003832 A Canadian multi-centre, open-label long-term study of Pegvisomant treatment in refractory acromegaly. 2009 Dec 1 2
83 20009494 Comparison of pegvisomant and long-acting octreotide in patients with acromegaly naïve to radiation and medical therapy. 2009 Dec 4
84 18031320 Pegvisomant-primed GH stimulation test. 2008 Jun 1
85 18431372 Long-term effects of pegvisomant in patients with acromegaly. 2008 Jun 1
86 18492755 Treatment of pituitary gigantism with the growth hormone receptor antagonist pegvisomant. 2008 Aug 1
87 18611977 Lipodystrophy in patients with acromegaly receiving pegvisomant. 2008 Sep 2
88 18617577 Growth hormone excess and the development of growth hormone receptor antagonists. 2008 Nov 1
89 18766168 Additional metabolic effects of adding GH receptor antagonist to long-acting somatostatin analog in patients with active acromegaly. 2008 Aug 1
90 17077131 Gender, body weight, disease activity, and previous radiotherapy influence the response to pegvisomant. 2007 Jan 8
91 17105844 Treatment with growth hormone receptor antagonist in acromegaly: effect on cardiac structure and performance. 2007 Feb 1
92 17218728 Treatment of acromegaly with the GH receptor antagonist pegvisomant in clinical practice: safety and efficacy evaluation from the German Pegvisomant Observational Study. 2007 Jan 1
93 17289896 Clinical pharmacodynamic effects of the growth hormone receptor antagonist pegvisomant: implications for cancer therapy. 2007 Feb 1 4
94 17341562 The impact of pegvisomant treatment on substrate metabolism and insulin sensitivity in patients with acromegaly. 2007 May 2
95 17427111 Pegvisomant treatment in gigantism caused by a growth hormone-secreting giant pituitary adenoma. 2007 Mar 2
96 17431794 Serum IGF-I levels in the diagnosis and monitoring of acromegaly. 2007 1
97 17534717 Pituitary tumor enlargement in two patients with acromegaly during pegvisomant therapy. 2007 2
98 17982395 McCune-Albright syndrome in adulthood. 2007 Aug 1
99 18058730 The medical treatment of acromegaly. 2007 Jul-Aug 2
100 18058736 [Pegvisomant--growth hormone receptor antagonist in the treatment of acromegaly]. 2007 Sep-Oct 2