| 1 |
31278717 | Hepatoprotective effect of ketoconazole in chronic liver injury model. | 2019 May |
1 |
| 2 |
28436281 | Terfenadine t-butyl hydroxylation catalyzed by human and marmoset cytochrome P450 3A and 4F enzymes in livers and small intestines. | 2018 Apr |
1 |
| 3 |
30072626 | Exploring the Metabolism of Loxoprofen in Liver Microsomes: The Role of Cytochrome P450 and UDP-Glucuronosyltransferase in Its Biotransformation. | 2018 Aug 2 |
1 |
| 4 |
28185143 | Characterization of 1-Aminobenzotriazole and Ketoconazole as Novel Inhibitors of Monoamine Oxidase (MAO): An In Vitro Investigation. | 2017 Oct |
3 |
| 5 |
27063220 | An improved substrate cocktail for assessing direct inhibition and time-dependent inhibition of multiple cytochrome P450s. | 2016 May |
1 |
| 6 |
27718490 | Improvement of the chemical inhibition phenotyping assay by cross-reactivity correction. | 2016 Dec 1 |
1 |
| 7 |
25864949 | A simple construction of electrochemical liver microsomal bioreactor for rapid drug metabolism and inhibition assays. | 2015 |
2 |
| 8 |
22426195 | Increased brain uptake of docetaxel and ketoconazole loaded folate-grafted solid lipid nanoparticles. | 2013 Jan |
1 |
| 9 |
24117377 | Cytochrome P450 modified polycrystalline indium tin oxide film as a drug metabolizing electrochemical biosensor with a simple configuration. | 2013 Nov 5 |
1 |
| 10 |
21704641 | Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes. | 2011 Aug 1 |
1 |
| 11 |
20437462 | Contributions of human cytochrome P450 enzymes to glyburide metabolism. | 2010 May |
1 |
| 12 |
16365879 | UVB-induced production of 1,25-dihydroxyvitamin D3 and vitamin D activity in human keratinocytes pretreated with a sterol delta7-reductase inhibitor. | 2006 May 1 |
1 |
| 13 |
20945304 | Human cytochrome P450: metabolism of testosterone by CYP3A4 and inhibition by ketoconazole. | 2004 Jun |
1 |
| 14 |
12388057 | TNF-alpha -induced endothelial cell adhesion molecule expression is cytochrome P-450 monooxygenase dependent. | 2003 Feb |
1 |
| 15 |
12599212 | Cyclooxygenase and cytochrome P-450 pathways induced by fetal calf serum regulate wound closure in 3T6 fibroblast cultures through the effect of prostaglandin E2 and 12 and 20 hydroxyeicosatetraenoic acids. | 2003 Apr |
2 |
| 16 |
15618748 | In vitro inhibitory effect of 1-aminobenzotriazole on drug oxidations catalyzed by human cytochrome P450 enzymes: a comparison with SKF-525A and ketoconazole. | 2003 |
2 |
| 17 |
11869873 | Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. | 2002 Apr |
1 |
| 18 |
11274000 | Endothelium-derived hyperpolarizing factor : identification and mechanisms of action in human subcutaneous resistance arteries. | 2001 Mar 27 |
1 |
| 19 |
9600717 | Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man. | 1998 Mar |
2 |
| 20 |
9694927 | Blockade of HERG and Kv1.5 by ketoconazole. | 1998 Aug |
1 |
| 21 |
16535142 | Microbial Demethylation of Immunosuppressant FK-506: Isolation of 31-O-FK-506-Specific Demethylase Showing Cytochrome P-450 Characteristics from Streptomyces rimosus MA187. | 1995 Oct |
1 |
| 22 |
7519397 | Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid conversion. | 1994 Jul |
1 |
| 23 |
7808019 | Clinical pharmacology of all-trans retinoic acid. | 1994 |
1 |
| 24 |
7967726 | Clinical pharmacology of all-trans retinoic acid. | 1994 Nov |
1 |
| 25 |
8068004 | Pharmacology of a Ca(2+)-influx pathway activated by emptying the intracellular Ca2+ stores in HL-60 cells: evidence that a cytochrome P-450 is not involved. | 1994 Aug 15 |
1 |
| 26 |
8230282 | Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans-retinoic acid, and its modulation by ketoconazole. | 1993 Dec 1 |
2 |
| 27 |
8411129 | Necturus gallbladder epithelial cell volume regulation and inhibitors of arachidonic acid metabolism. | 1993 Jul |
1 |
| 28 |
1311943 | Azoles, allylamines and drug metabolism. | 1992 Feb |
1 |
| 29 |
1328295 | Human skin levels of retinoic acid and cytochrome P-450-derived 4-hydroxyretinoic acid after topical application of retinoic acid in vivo compared to concentrations required to stimulate retinoic acid receptor-mediated transcription in vitro. | 1992 Oct |
1 |
| 30 |
1458471 | Effects of ketoconazole on the proliferation and cell cycle of human cancer cell lines. | 1992 Dec 15 |
2 |
| 31 |
1510705 | Primaquine metabolism by human liver microsomes: effect of other antimalarial drugs. | 1992 Aug 4 |
1 |
| 32 |
1550407 | Differential metabolism of 25-hydroxyvitamin D3 by cultured synovial fluid macrophages and fibroblast-like cells from patients with arthritis. | 1992 Feb |
1 |
| 33 |
1596283 | Mefloquine metabolism by human liver microsomes. Effect of other antimalarial drugs. | 1992 May 8 |
2 |
| 34 |
1811554 | Effects of gemfibrozil and ketoconazole on human apolipoprotein AI, B and E levels in two hepatoma cell lines, HepG2 and Hep3B. | 1991 Nov |
1 |
| 35 |
2214784 | In vitro inhibition by ketoconazole of human testicular steroid oxidoreductases. | 1990 Aug 28 |
2 |
| 36 |
2763709 | [Detoxifying function of the liver in patients with rubromycosis during treatment with antimycotics]. | 1989 |
1 |
| 37 |
2775621 | Effects of ketoconazole on the polymorphic 4-hydroxylations of S-mephenytoin and debrisoquine. | 1989 Aug |
1 |
| 38 |
2848984 | Effects of two oral antimycotics, ketoconazole and fluconazole, upon steroidogenesis in rat adrenal cells in vitro. | 1988 Nov |
1 |
| 39 |
3027305 | Differential effects of the imidazole derivatives etomidate, ketoconazole and miconazole and of metyrapone on the secretion of cortisol and its precursors by human adrenocortical cells. | 1987 Jan |
1 |
| 40 |
3030012 | Interaction of miconazole, ketoconazole and itraconazole with rat-liver microsomes. | 1987 Jan |
2 |
| 41 |
3036162 | Effect of ketoconazole on cholesterol synthesis and on HMG-CoA reductase and LDL-receptor activities in Hep G2 cells. | 1987 Apr 15 |
1 |
| 42 |
3111839 | Ketoconazole as a possible universal inhibitor of cytochrome P-450 dependent enzymes: its mode of inhibition. | 1987 Feb |
7 |
| 43 |
3331377 | Effects of drug administration on gonadotropins, sex steroid hormones and binding proteins in humans. | 1987 |
1 |
| 44 |
3025521 | Effect of ketoconazole on placental aromatase, 3 beta-hydroxysteroid dehydrogenase-isomerase and 17 beta-hydroxysteroid dehydrogenase. | 1986 Dec |
2 |