Title : Primaquine metabolism by human liver microsomes: effect of other antimalarial drugs.

Pub. Date : 1992 Aug 4

PMID : 1510705






1 Functional Relationships(s)
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1 Ketoconazole, a known inhibitor of cytochrome P450 isozymes, caused marked inhibition of carboxyprimaquine formation with IC50 and K(i) values of 15 and 6.7 microM, respectively. Ketoconazole cytochrome P450 family 4 subfamily F member 3 Homo sapiens