Ketoconazole

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







17 Article(s)
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Pub. Year
#Total Relationships
1 26655108 Comparison of enzyme kinetics of warfarin analyzed by LC-MS/MS QTrap and differential mobility spectrometry. 2016 Jan 1 1
2 24174816 Inhibitory effect of mitragynine on human cytochrome P450 enzyme activities. 2013 Oct 1
3 22022918 Ilaprazole, a new proton pump inhibitor, is primarily metabolized to ilaprazole sulfone by CYP3A4 and 3A5. 2012 Mar 1
4 21277363 Involvement of CYP3A4/5 and CYP2D6 in the metabolism of aconitine using human liver microsomes and recombinant CYP450 enzymes. 2011 Apr 10 1
5 21550074 Ritonavir inhibits the two main prasugrel bioactivation pathways in vitro: a potential drug-drug interaction in HIV patients. 2011 Nov 1
6 18950609 Metabolism Comparative Cytotoxicity Assay (MCCA) and Cytotoxic Metabolic Pathway Identification Assay (CMPIA) with cryopreserved human hepatocytes for the evaluation of metabolism-based cytotoxicity in vitro: proof-of-concept study with aflatoxin B1. 2009 Apr 15 1
7 16556082 Drug interactions during therapy with three major groups of antimicrobial agents. 2006 Apr 1
8 14709627 Highly selective inhibition of human CYP3Aa in vitro by azamulin and evidence that inhibition is irreversible. 2004 Jan 1
9 15304426 The involvement of CYP3A4 and CYP2C9 in the metabolism of 17 alpha-ethinylestradiol. 2004 Nov 1
10 15373932 Effect of ketoconazole on the pharmacokinetics of rosiglitazone in healthy subjects. 2004 Oct 1
11 11854151 Inhibition of cytochromes P450 by antifungal imidazole derivatives. 2002 Mar 1
12 9925971 In vitro biotransformation of a novel antimalarial cysteine protease inhibitor in human liver microsomes. 1999 Mar 1
13 10078840 Fully automated analysis of activities catalysed by the major human liver cytochrome P450 (CYP) enzymes: assessment of human CYP inhibition potential. 1999 Jan 1
14 10418968 Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential. 1999 Jun 1 1
15 9531525 Overlapping substrate specificities of cytochrome P450 3A and P-glycoprotein for a novel cysteine protease inhibitor. 1998 Apr 1
16 9037249 Variable contribution of cytochromes P450 2D6, 2C9 and 3A4 to the 4-hydroxylation of tamoxifen by human liver microsomes. 1997 Jan 24 1
17 9353355 Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples. 1997 Nov 1