Tyrosine

CD2 molecule ; Homo sapiens







54 Article(s)
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1 24371564 Diversity of CD2 subfamily receptors in cyprinid fishes. 2012 1
2 16177091 Phosphotyrosine binding-mediated oligomerization of downstream of tyrosine kinase (Dok)-1 and Dok-2 is involved in CD2-induced Dok phosphorylation. 2005 Oct 1 1
3 11792427 Role for adapter proteins in costimulatory signals of CD2 and IL-2 on NK cell activation. 2002 Jan 3
4 12163161 The proline rich region of the Tec homology domain of ITK regulates its activity. 2002 Aug 14 1
5 11133830 The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation. 2001 Jan 3
6 11166460 CD2 stimulation leads to the delayed and prolonged activation of STAT1 in T cells but not NK cells. 2001 Feb 1
7 11254695 p62dok negatively regulates CD2 signaling in Jurkat cells. 2001 Apr 1 1
8 11376005 Dynamic recruitment of human CD2 into lipid rafts. Linkage to T cell signal transduction. 2001 Jun 1 1
9 11513145 2B4 (CD244) and CS1: novel members of the CD2 subset of the immunoglobulin superfamily molecules expressed on natural killer cells and other leukocytes. 2001 Jun 1
10 11553620 T cell regulation of p62(dok) (Dok1) association with Crk-L. 2001 Dec 7 2
11 11555388 CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes. 2001 Sep 1
12 10979964 Signaling via LAT (linker for T-cell activation) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation. 2000 Sep 15 3
13 11093148 Priming of CD2-induced p62Dok tyrosine phosphorylation by CD3 in Jurkat T cells. 2000 Nov 6
14 11399323 Differential interaction of Cbl with Grb2 and CrkL in CD2-mediated NK cell activation. 2000 Dec 3
15 10510361 CD2 and CD3 associate independently with CD5 and differentially regulate signaling through CD5 in Jurkat T cells. 1999 Oct 15 1
16 10586033 Regulated association between the tyrosine kinase Emt/Itk/Tsk and phospholipase-C gamma 1 in human T lymphocytes. 1999 Dec 15 1
17 9677430 Association of p59(fyn) with the T lymphocyte costimulatory receptor CD2. Binding of the Fyn Src homology (SH) 3 domain is regulated by the Fyn SH2 domain. 1998 Jul 31 3
18 9678765 Co-stimulation of T cells with CD2 augments TCR-CD3-mediated activation of protein tyrosine kinase p72syk, resulting in increased tyrosine phosphorylation of adapter proteins, Shc and Cbl. 1998 Jun 8
19 9701039 CD2-mediated activation of the Tec-family tyrosine kinase ITK is controlled by proline-rich stretch-4 of the CD2 cytoplasmic tail. 1998 Jul 1
20 9794375 Uncoupling activation-dependent HS1 phosphorylation from nuclear factor of activated T cells transcriptional activation in Jurkat T cells: differential signaling through CD3 and the costimulatory receptors CD2 and CD28. 1998 Nov 1 1
21 9862370 Signaling through the tetraspanin CD82 triggers its association with the cytoskeleton leading to sustained morphological changes and T cell activation. 1998 Dec 1
22 9130632 Itk, a T cell-specific tyrosine kinase, is required for CD2-mediated interleukin-2 promoter activation in the human T cell line Jurkat. 1997 Apr 1
23 9233614 Involvement of protein tyrosine kinase p72syk and phosphatidylinositol 3-kinase in CD2-mediated granular exocytosis in the natural killer cell line, NK3.3. 1997 Aug 1 2
24 9341764 CD2-mediated signaling in T cells lacking the zeta-chain-specific immune receptor tyrosine-based activation (ITAM) motif. 1997 Sep 2
25 9548475 Structural requirements for beta1 integrin-mediated tyrosine phosphorylation in human T cells. 1997 Dec 1 2
26 8558013 CD28-mediated up-regulation of beta 1-integrin adhesion involves phosphatidylinositol 3-kinase. 1996 Feb 1 1
27 8617939 CD2-induced apoptosis in activated human peripheral T cells: a Fas-independent pathway that requires early protein tyrosine phosphorylation. 1996 May 1 1
28 8660853 Focal adhesion kinase-related fakB is regulated by the integrin LFA-1 and interacts with the SH3 domain of phospholipase C gamma 1. 1996 Jul 10 1
29 8906806 Tyrosine phosphorylation and recruitment of ZAP-70 to the CD3-TCR complex are defective after CD2 stimulation. 1996 Nov 15 5
30 8943565 CD2 signaling in T cells involves tyrosine phosphorylation and activation of the Tec family kinase, EMT/ITK/TSK. 1996 Nov 3
31 7621876 The role of lymphocyte subsets and adhesion molecules in T cell-dependent cytotoxicity mediated by CD3 and CD28 bispecific monoclonal antibodies. 1995 Jul 1
32 7739570 Differential regulation of accessory mitogenic signaling receptors by the T cell antigen receptor. 1995 Apr 1
33 7519476 Maturation of acute T-lymphoblastic leukemia cells after CD2 ligation and subsequent treatment with interleukin-2. 1994 Aug 15 1
34 7524094 Lymphocyte antigen receptor activation of a focal adhesion kinase-related tyrosine kinase substrate. 1994 Oct 25 1
35 7526919 P56lck: a transducing protein that binds to SH2 containing proteins and to phosphotyrosine containing proteins. 1994 Jul 1
36 7930601 Contribution of tyrosine kinases to the selective orientation of human CD4+ bifunctional cloned T cells toward proliferation or cytolytic function. 1994 Nov 1 2
37 7981618 P56lck A lymphocyte specific protein tyrosine kinase: activation, regulation and signal transduction. 1994 Jul 1
38 8208538 Vav binds to several SH2/SH3 containing proteins in activated lymphocytes. 1994 Jul 1
39 7678115 Tyrosine phosphorylation of CD6 by stimulation of CD3: augmentation by the CD4 and CD2 coreceptors. 1993 Jan 1 4
40 7688073 Comparative analysis of phosphotyrosyl polypeptides in normal and leukemic human T lymphocytes activated via CD3 or CD2. 1993 Jul 2
41 7693851 Tyrosine phosphorylation and association with phospholipase C gamma-1 of the GAP-associated 62-kD protein after CD2 stimulation of Jurkat T cell. 1993 Nov 1 7
42 7902214 Regulation of CD2-mediated human T cell activation: anti-CD8 monoclonal antibodies inhibit CD2-mediated rise in intracellular calcium. 1993 Nov 2
43 7903276 Concurrent strong tyrosine phosphorylation of a 42,000 MW ERK and a 100,000 MW protein is associated with IL-2 production in human Jurkat T cells. 1993 Oct 4
44 8093441 Alterations of CD2 association with T cell receptor signaling molecules in "CD2 unresponsive" human T lymphocytes. 1993 Jan 1
45 8096437 Anti-CD2-induced tyrosine phosphorylation of T cell polypeptides is independent of the PMA-induced modification of p56lck. 1993 Mar 5
46 1372020 CD2/LFA-3 ligation induces phospholipase-C gamma 1 tyrosine phosphorylation and regulates CD3 signaling. 1992 Apr 1 5
47 1673433 CD2 is functionally linked to the zeta-natural killer receptor complex. 1991 Apr 1
48 1678351 The tyrosine kinase activity of p56lck is increased in human T cells activated via CD2. 1991 Aug 1
49 1679714 The T cell receptor/CD3 complex and CD2 stimulate the tyrosine phosphorylation of indistinguishable patterns of polypeptides in the human T leukemic cell line Jurkat. 1991 Sep 1
50 1688586 Activation of human T lymphocytes via the CD2 antigen results in tyrosine phosphorylation of T cell antigen receptor zeta-chains. 1990 Feb 1 2