Pub. Date : 2002 Jan
PMID : 11792427
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CD2 crosslinking markedly induced tyrosine phosphorylation of Cbl associated with Grb2 or CrkL, Shc and LAT, compared with IL-2 stimulation. | Tyrosine | CD2 molecule | Homo sapiens |
| 2 | Furthermore, CD2 crosslinking, but not IL-2 stimulation, markedly induced tyrosine phosphorylation of LAT. | Tyrosine | CD2 molecule | Homo sapiens |
| 3 | Thus, tyrosine phosphorylation of different adapter proteins and consequent interactions between signaling molecules described here may explain the molecular mechanisms of the additive effects of IL-2 stimulation and CD2 crosslinking on NK cell activation. | Tyrosine | CD2 molecule | Homo sapiens |