Pub. Date : 2000 Nov
PMID : 11093148
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Priming of CD2-induced p62Dok tyrosine phosphorylation by CD3 in Jurkat T cells. | Tyrosine | CD2 molecule | Homo sapiens |
| 2 | Beside common biochemical events, we previously showed that a 62-kDa protein associated with PLCgamma-1 and p21RasGAP was specifically tyrosine phosphorylated after CD2 stimulation in Jurkat T cells. | Tyrosine | CD2 molecule | Homo sapiens |
| 3 | Mainly, we showed that p62Dok tyrosine phosphorylation was strengthened by the functional interplay between CD3 and CD2. | Tyrosine | CD2 molecule | Homo sapiens |
| 4 | Kinetic studies indicated that a short treatment with anti-CD3 was sufficient to amplify the CD2-induced tyrosine phosphorylation of p62Dok. | Tyrosine | CD2 molecule | Homo sapiens |
| 5 | By contrast, CD2-induced PLCgamma-1 tyrosine phosphorylation and calcium response progressively diminished. | Tyrosine | CD2 molecule | Homo sapiens |
| 6 | Finally, enhanced amounts of tyrosine phosphorylated p62Dok were recruited to p21RasGAP and PLCgamma-1 after CD2 stimulation in CD3-activated cells. | Tyrosine | CD2 molecule | Homo sapiens |