| 1 |
34380995 | Pharmacogenetic study of methadone treatment for heroin addiction: associations between drug-metabolizing gene polymorphisms and treatment efficacy. | 2022 Jan 1 |
1 |
| 2 |
35194103 | CYP2B6 allelic variants and non-genetic factors influence CYP2B6 enzyme function. | 2022 Feb 22 |
1 |
| 3 |
35356868 | Impact of liver fibrosis and clinical characteristics on dose-adjusted serum methadone concentrations. | 2022 Mar 31 |
1 |
| 4 |
35538637 | Methadone pharmacogenetics in vitro and in vivo: Metabolism by CYP2B6 polymorphic variants and genetic variability in paediatric disposition. | 2022 May 10 |
8 |
| 5 |
32841585 | Pharmacogenomics biomarkers for personalized methadone maintenance treatment: The mechanism and its potential use. | 2021 Apr 1 |
4 |
| 6 |
33546554 | Investigating the CYP2B6 rs3745274 and rs3211371 polymorphisms in Methadone-Responder and Non-Responder Addicts in Iran. | 2021 Feb 6 |
4 |
| 7 |
33599403 | Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population. | 2021 Mar |
1 |
| 8 |
34100292 | Novel associations between CYP2B6 polymorphisms, perioperative methadone metabolism and clinical outcomes in children. | 2021 Jul |
2 |
| 9 |
34482033 | Effect of HIV, antiretrovirals, and genetics on methadone pharmacokinetics: Results from the methadone antiretroviral pharmacokinetics study. | 2021 Oct 1 |
1 |
| 10 |
34910759 | Implications of OPRM1 and CYP2B6 variants on treatment outcomes in methadone-maintained patients in Ontario: Exploring sex differences. | 2021 |
4 |
| 11 |
32302325 | Toward precision prescribing for methadone: Determinants of methadone deposition. | 2020 |
3 |
| 12 |
32564328 | Methadone for Pain Management: A Pharmacotherapeutic Review. | 2020 Aug |
3 |
| 13 |
32870067 | Population Pharmacokinetics of Methadone after Oral Administration in Japanese Patients with Cancer-Related Pain. | 2020 Dec |
1 |
| 14 |
30906561 | Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes. | 2019 Apr |
1 |
| 15 |
30907440 | Relevance of CYP2B6 and CYP2D6 genotypes to methadone pharmacokinetics and response in the OPAL study. | 2019 Jul |
5 |
| 16 |
30973652 | Drug-Drug Interaction Studies of Methadone and Antiviral Drugs: Lessons Learned. | 2019 Aug |
3 |
| 17 |
29458047 | Effects of cytochrome P450 single nucleotide polymorphisms on methadone metabolism and pharmacodynamics. | 2018 Jul |
8 |
| 18 |
30201214 | Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation. | 2018 Oct |
2 |
| 19 |
30205091 | Methadone Metabolism and Drug-Drug Interactions: In Vitro and In Vivo Literature Review. | 2018 Dec |
2 |
| 20 |
28184434 | Tell-Tale SNPs: The Role of CYP2B6 in Methadone Fatalities. | 2017 May 1 |
3 |
| 21 |
28263461 | Current Concepts in Methadone Metabolism and Transport. | 2017 Mar |
8 |
| 22 |
28320034 | Variations in Infant CYP2B6 Genotype Associated with the Need for Pharmacological Treatment for Neonatal Abstinence Syndrome in Infants of Methadone-Maintained Opioid-Dependent Mothers. | 2017 Jul |
1 |
| 23 |
28699698 | Reduced dosing and liability in methadone maintenance treatment by targeting oestrogen signal for morphine addiction. | 2017 Dec |
1 |
| 24 |
28723731 | Combined Effect of CYP2B6 Genotype and Other Candidate Genes on a Steady-State Serum Concentration of Methadone in Opioid Maintenance Treatment. | 2017 Oct |
5 |
| 25 |
29302220 | A brief review of the genetics and pharmacogenetics of opioid use disorders. | 2017 Sep |
4 |
| 26 |
27010727 | Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients. | 2016 Mar |
3 |
| 27 |
27286724 | Population Genetic-Based Pharmacokinetic Modeling of Methadone and its Relationship with the QTc Interval in Opioid-Dependent Patients. | 2016 Dec |
2 |
| 28 |
27289271 | Relationship between CYP2B6*6 and cold pressor pain sensitivity in opioid dependent patients on methadone maintenance therapy (MMT). | 2016 Aug 1 |
3 |
| 29 |
27515451 | CYP2B6 and OPRM1 Receptor Polymorphisms at Methadone Clinics And Novel OPRM1 Haplotypes: A Cross-Sectional Study. | 2016 |
3 |
| 30 |
27709010 | Insights into CYP2B6-mediated drug-drug interactions. | 2016 Sep |
1 |
| 31 |
25801005 | Influence of HIV antiretrovirals on methadone N-demethylation and transport. | 2015 May 15 |
2 |
| 32 |
25897175 | Differences in Methadone Metabolism by CYP2B6 Variants. | 2015 Jul |
15 |
| 33 |
26227254 | Metabolism and Disposition of Prescription Opioids: A Review. | 2015 Jul |
1 |
| 34 |
26389554 | Methadone Pharmacogenetics: CYP2B6 Polymorphisms Determine Plasma Concentrations, Clearance, and Metabolism. | 2015 Nov |
17 |
| 35 |
23834474 | Expansion of a PBPK model to predict disposition in pregnant women of drugs cleared via multiple CYP enzymes, including CYP2B6, CYP2C9 and CYP2C19. | 2014 Mar |
1 |
| 36 |
24489693 | Impact of ABCB1 and CYP2B6 genetic polymorphisms on methadone metabolism, dose and treatment response in patients with opioid addiction: a systematic review and meta-analysis. | 2014 |
6 |
| 37 |
25456329 | Ethnic and genetic factors in methadone pharmacokinetics: a population pharmacokinetic study. | 2014 Dec 1 |
1 |
| 38 |
21790905 | CYP2B6 SNPs are associated with methadone dose required for effective treatment of opioid addiction. | 2013 Jul |
5 |
| 39 |
22815312 | Quantitative prediction of CYP2B6 induction by estradiol during pregnancy: potential explanation for increased methadone clearance during pregnancy. | 2013 Feb |
1 |
| 40 |
22926004 | Pharmacologic evidence to support clinical decision making for peripartum methadone treatment. | 2013 Jan |
1 |
| 41 |
23249875 | Contribution of CYP2B6 alleles in explaining extreme (S)-methadone plasma levels: a CYP2B6 gene resequencing study. | 2013 Feb |
7 |
| 42 |
23288240 | PXR polymorphisms interacted with CYP2B6 polymorphisms on methadone metabolites. | 2013 Feb |
1 |
| 43 |
23298862 | Methadone N-demethylation by the common CYP2B6 allelic variant CYP2B6.6. | 2013 Apr |
23 |
| 44 |
23361846 | Role of cytochrome P4502B6 in methadone metabolism and clearance. | 2013 Mar |
9 |
| 45 |
23467454 | Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance. | 2013 |
1 |
| 46 |
23733841 | Mechanism of autoinduction of methadone N-demethylation in human hepatocytes. | 2013 Jul |
4 |
| 47 |
24455721 | Moving toward personalized medicine in the methadone maintenance treatment program: a pilot study on the evaluation of treatment responses in Taiwan. | 2013 |
1 |
| 48 |
25278738 | Pharmacogenomics study in a Taiwan methadone maintenance cohort. | 2013 Dec |
3 |
| 49 |
22398970 | Mechanism of efavirenz influence on methadone pharmacokinetics and pharmacodynamics. | 2012 Apr |
2 |
| 50 |
22511698 | Evaluating the relationship of methadone concentrations and EDDP formation in chronic pain patients. | 2012 May |
1 |