Triglycerides

stearoyl-Coenzyme A desaturase 1 ; Mus musculus







46 Article(s)
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1 32978274 SCD1 promotes lipid mobilization in subcutaneous white adipose tissue. 2020 Dec 2
2 32982112 Arachidyl amido cholanoic acid improves liver glucose and lipid homeostasis in nonalcoholic steatohepatitis via AMPK and mTOR regulation. 2020 Sep 14 2
3 33374300 Interplay between Thyroid Hormones and Stearoyl-CoA Desaturase 1 in the Regulation of Lipid Metabolism in the Heart. 2020 Dec 24 3
4 31226399 Berberine attenuates nonalcoholic hepatic steatosis through the AMPK-SREBP-1c-SCD1 pathway. 2019 Sep 1
5 31729980 FoxO3 regulates hepatic triglyceride metabolism via modulation of the expression of sterol regulatory-element binding protein 1c. 2019 Nov 15 1
6 28982014 The role of suppression of hepatic SCD1 expression in the metabolic effects of dietary methionine restriction. 2018 Feb 1
7 29759071 Metformin attenuates triglyceride accumulation in HepG2 cells through decreasing stearyl-coenzyme A desaturase 1 expression. 2018 May 14 5
8 27846372 Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells. 2017 Jan 2 2
9 28190475 Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor. 2017 Feb 15 1
10 28789977 Ablation of systemic SIRT1 activity promotes nonalcoholic fatty liver disease by affecting liver-mesenteric adipose tissue fatty acid mobilization. 2017 Nov 1
11 29159325 Role of Aramchol in steatohepatitis and fibrosis in mice. 2017 Nov 2
12 26687933 Leucine supplementation via drinking water reduces atherosclerotic lesions in apoE null mice. 2016 Feb 1
13 27627966 Tlr4-mutant mice are resistant to acute alcohol-induced sterol-regulatory element binding protein activation and hepatic lipid accumulation. 2016 Sep 15 1
14 27751891 Stearoyl-CoA desaturase 1 deficiency reduces lipid accumulation in the heart by activating lipolysis independently of peroxisome proliferator-activated receptor α. 2016 Dec 1
15 25959085 SCD1 inhibition during 3T3-L1 adipocyte differentiation remodels triacylglycerol, diacylglycerol and phospholipid fatty acid composition. 2015 Jul 1
16 26219821 Moderate activation of IKK2-NF-kB in unstressed adult mouse liver induces cytoprotective genes and lipogenesis without apparent signs of inflammation or fibrosis. 2015 Jul 30 1
17 26690553 Diet rich in Docosahexaenoic Acid/Eicosapentaenoic Acid robustly ameliorates hepatic steatosis and insulin resistance in seipin deficient lipodystrophy mice. 2015 2
18 24566853 Inhibition of stearoyl-CoA desaturase-1 in differentiating 3T3-L1 preadipocytes upregulates elongase 6 and downregulates genes affecting triacylglycerol synthesis. 2014 Nov 3
19 24773344 The Niemann-Pick C1 like 1 (NPC1L1) inhibitor ezetimibe improves metabolic disease via decreased liver X receptor (LXR) activity in liver of obese male mice. 2014 Aug 1
20 23918045 SCD1 activity in muscle increases triglyceride PUFA content, exercise capacity, and PPARδ expression in mice. 2013 Oct 3
21 23941875 Role of stearoyl-CoA desaturase-1 in skeletal muscle function and metabolism. 2013 Oct 1 2
22 21609322 PPARα-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status. 2011 Aug 1 1
23 21890736 Aryl hydrocarbon receptor-mediated induction of Stearoyl-CoA desaturase 1 alters hepatic fatty acid composition in TCDD-elicited steatosis. 2011 Dec 1
24 20363835 Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice. 2010 Aug 1
25 19095997 Despite antiatherogenic metabolic characteristics, SCD1-deficient mice have increased inflammation and atherosclerosis. 2009 Mar 2
26 20029635 The Decrease of n-3 Fatty Acid Energy Percentage in an Equicaloric Diet Fed to B6C3Fe Mice for Three Generations Elicits Obesity. 2009 2
27 17960025 Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice. 2008 Jan 1
28 18340007 Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia. 2008 Jun 3
29 18794388 Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis. 2008 Sep 30 1
30 17605312 Stearoyl-CoA desaturase deficiency, hypercholesterolemia, cholestasis, and diabetes. 2007 Jun 1
31 18269173 Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes. 2007 2
32 16537646 CREB activation induced by mitochondrial dysfunction triggers triglyceride accumulation in 3T3-L1 preadipocytes. 2006 Apr 1 1
33 16751624 Colocalization of SCD1 and DGAT2: implying preference for endogenous monounsaturated fatty acids in triglyceride synthesis. 2006 Sep 8
34 16943421 Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation. 2006 Sep 1
35 15494611 Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue. 2005 Feb 1
36 15761499 Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1. 2005 Apr 2
37 15829484 Stearoyl-CoA desaturase 1 deficiency increases CTP:choline cytidylyltransferase translocation into the membrane and enhances phosphatidylcholine synthesis in liver. 2005 Jun 17 1
38 15066988 Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms. 2004 Jun 11 1
39 15657555 Microarrays, antiobesity and the liver. 2004 Oct-Dec 1
40 12114623 Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. 2002 Jul 12 1
41 12177411 Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. 2002 Aug 20 1
42 12364560 Dietary cholesterol opposes PUFA-mediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism. 2002 Oct 1
43 12401889 Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia. 2002 Nov 1
44 11441127 A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis. 2001 Jul 4
45 11533264 Targeted disruption of stearoyl-CoA desaturase1 gene in mice causes atrophy of sebaceous and meibomian glands and depletion of wax esters in the eyelid. 2001 Sep 3
46 10899171 The biosynthesis of hepatic cholesterol esters and triglycerides is impaired in mice with a disruption of the gene for stearoyl-CoA desaturase 1. 2000 Sep 29 7