Title : Tlr4-mutant mice are resistant to acute alcohol-induced sterol-regulatory element binding protein activation and hepatic lipid accumulation.

Pub. Date : 2016 Sep 15

PMID : 27627966






1 Functional Relationships(s)
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Protein Name
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1 Hepatic Fas, Acc, Scd-1 and Dgat-2, the key genes for fatty acid and TG synthesis, were up-regulated in alcohol-treated Tlr4-wild-type mice but not in Tlr4-mutant mice. Triglycerides stearoyl-Coenzyme A desaturase 1 Mus musculus