Title : Ablation of systemic SIRT1 activity promotes nonalcoholic fatty liver disease by affecting liver-mesenteric adipose tissue fatty acid mobilization.

Pub. Date : 2017 Nov

PMID : 28789977






1 Functional Relationships(s)
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1 Sirt1Y/Y mice showed significantly higher level of hepatic triglyceride which was accompanied with higher levels of SREBP-1 and SCD1and decreased phosphorylation of LKB1 and AMPK in the liver. Triglycerides stearoyl-Coenzyme A desaturase 1 Mus musculus