| 1 |
33762326 | The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway. | 2021 Apr 15 |
1 |
| 2 |
30979377 | NDR2 kinase contributes to cell invasion and cytokinesis defects induced by the inactivation of RASSF1A tumor-suppressor gene in lung cancer cells. | 2019 Apr 12 |
1 |
| 3 |
29718126 | Relapse pathway of glioblastoma revealed by single-cell molecular analysis. | 2018 Jul 3 |
1 |
| 4 |
28706196 | Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling. | 2017 Jul 13 |
1 |
| 5 |
29106825 | Recurrent De Novo Mutations Disturbing the GTP/GDP Binding Pocket of RAB11B Cause Intellectual Disability and a Distinctive Brain Phenotype. | 2017 Nov 2 |
1 |
| 6 |
27458535 | Modulation of B-cell receptor and microenvironment signaling by a guanine exchange factor in B-cell malignancies. | 2016 Jun |
1 |
| 7 |
27558716 | Nanosecond Dynamics of Gαi1 Bound to Nucleotides or Ric-8A, a Gα Chaperone with GEF Activity. | 2016 Aug 23 |
1 |
| 8 |
25707436 | GTP-specific fab fragment-based GTPase activity assay. | 2015 Mar 17 |
1 |
| 9 |
25825487 | Combined rational design and a high throughput screening platform for identifying chemical inhibitors of a Ras-activating enzyme. | 2015 May 15 |
1 |
| 10 |
26195453 | A High-Throughput Assay for Rho Guanine Nucleotide Exchange Factors Based on the Transcreener GDP Assay. | 2015 Dec |
2 |
| 11 |
26304119 | MYCBP2 Is a Guanosine Exchange Factor for Ran Protein and Determines Its Localization in Neurons of Dorsal Root Ganglia. | 2015 Oct 16 |
1 |
| 12 |
26488653 | Effect of the N-Terminal Helix and Nucleotide Loading on the Membrane and Effector Binding of Arl2/3. | 2015 Oct 20 |
1 |
| 13 |
24597981 | Amplification of B cell receptor-Erk signaling by Rasgrf-1 overexpression in chronic lymphocytic leukemia. | 2014 Dec |
2 |
| 14 |
24760397 | A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction. | 2014 Jul |
2 |
| 15 |
22960035 | Increased cell growth due to a new lipase-GEF (Phospholipase D2) fastly acting on Ras. | 2013 Jan |
2 |
| 16 |
22291991 | RINL, guanine nucleotide exchange factor Rab5-subfamily, is involved in the EphA8-degradation pathway with odin. | 2012 |
1 |
| 17 |
22673745 | Divergence of Rho residue 43 impacts GEF activity. | 2012 Jan-Mar |
2 |
| 18 |
22825554 | The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling. | 2012 Oct |
1 |
| 19 |
22847784 | GEF-H1 over-expression in hepatocellular carcinoma promotes cell motility via activation of RhoA signalling. | 2012 Dec |
1 |
| 20 |
23076143 | The many faces of the guanine-nucleotide exchange factor trio. | 2012 Nov-Dec |
1 |
| 21 |
21390270 | Nucleotide binding switches the information flow in ras GTPases. | 2011 Mar |
3 |
| 22 |
21454697 | Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C. | 2011 May 13 |
2 |
| 23 |
21494904 | Structural study of the Cdc25 domain from Ral-specific guanine-nucleotide exchange factor RalGPS1a. | 2011 Apr |
1 |
| 24 |
21586568 | Characterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31. | 2011 Jul 8 |
1 |
| 25 |
21828055 | Novel C-terminal motif within Sec7 domain of guanine nucleotide exchange factors regulates ADP-ribosylation factor (ARF) binding and activation. | 2011 Oct 21 |
1 |
| 26 |
19356586 | Characterisation of the nucleotide exchange factor ITSN1L: evidence for a kinetic discrimination of GEF-stimulated nucleotide release from Cdc42. | 2009 Mar 27 |
3 |
| 27 |
19361519 | Kinetic analysis of the guanine nucleotide exchange activity of TRAPP, a multimeric Ypt1p exchange factor. | 2009 Jun 5 |
1 |
| 28 |
19745154 | Activation of Rho GTPases by DOCK exchange factors is mediated by a nucleotide sensor. | 2009 Sep 11 |
1 |
| 29 |
18347012 | RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules. | 2008 May 16 |
1 |
| 30 |
18505730 | Dissociation of Rac1(GDP).RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP. | 2008 Aug 8 |
1 |
| 31 |
17488622 | GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases. | 2007 May |
2 |
| 32 |
17593019 | Regulation of type V adenylate cyclase by Ric8a, a guanine nucleotide exchange factor. | 2007 Sep 15 |
1 |
| 33 |
16257999 | GEF-H1 is involved in agonist-induced human pulmonary endothelial barrier dysfunction. | 2006 Mar |
1 |
| 34 |
16472645 | Purification and biochemical properties of Rac1, 2, 3 and the splice variant Rac1b. | 2006 |
1 |
| 35 |
15709769 | Mechanism of the guanine nucleotide exchange reaction of Ras GTPase--evidence for a GTP/GDP displacement model. | 2005 Feb 22 |
3 |
| 36 |
15850775 | Novel intermediate of Rac GTPase activation by guanine nucleotide exchange factor. | 2005 Jun 3 |
6 |
| 37 |
16248653 | Common semiopen conformations of Mg2+-free Ras, Rho, Rab, Arf, and Ran proteins combined with GDP and their similarity with GEF-bound forms. | 2005 Nov 2 |
2 |
| 38 |
14597635 | Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant. | 2004 Jan 30 |
1 |
| 39 |
14625275 | Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase. | 2004 Feb 6 |
1 |
| 40 |
14712228 | Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential. | 2004 Jan 8 |
1 |
| 41 |
15544329 | Oncogenic Dbl, Cdc42, and p21-activated kinase form a ternary signaling intermediate through the minimum interactive domains. | 2004 Nov 23 |
3 |
| 42 |
12641750 | Regulation of neuritogenesis and synaptic transmission by msec7-1, a guanine nucleotide exchange factor, in cultured Aplysia neurons. | 2003 Apr |
1 |
| 43 |
12680752 | Rational design of genetically encoded fluorescence resonance energy transfer-based sensors of cellular Cdc42 signaling. | 2003 Apr 15 |
1 |
| 44 |
11087745 | Phospholipase Cdelta1 is a guanine nucleotide exchanging factor for transglutaminase II (Galpha h) and promotes alpha 1B-adrenoreceptor-mediated GTP binding and intracellular calcium release. | 2001 Feb 23 |
2 |
| 45 |
9763446 | Identification of regulators for Ypt1 GTPase nucleotide cycling. | 1998 Oct |
1 |
| 46 |
9790530 | Structural basis for activation of ARF GTPase: mechanisms of guanine nucleotide exchange and GTP-myristoyl switching. | 1998 Oct 16 |
1 |
| 47 |
8756332 | Ras/Rap effector specificity determined by charge reversal. | 1996 Aug |
1 |
| 48 |
8589075 | Small G proteins and the neutrophil NADPH oxidase. | 1995 |
1 |
| 49 |
7581745 | Translational control of eukaryotic gene expression. Role of the guanine nucleotide exchange factor and chain initiation factor-2. | 1994-1995 |
2 |
| 50 |
8049218 | Phosphorylation of the guanine nucleotide exchange factor and eukaryotic initiation factor 2 by casein kinase II regulates guanine nucleotide binding and GDP/GTP exchange. | 1994 Aug 9 |
4 |