| 1 |
35325397 | Phosphorylation of Focal Adhesion Kinase at Y925: Role in Glia-Dependent and Independent Migration through Regulating Cofilin and N-Cadherin. | 2022 Jun |
2 |
| 2 |
32843133 | Pleckstrin homology domain of phospholipase D2 is a negative regulator of focal adhesion kinase. | 2021 Feb |
6 |
| 3 |
33314143 | Adhesion-dependent Caveolin-1 Tyrosine-14 phosphorylation is regulated by FAK in response to changing matrix stiffness. | 2021 Feb |
1 |
| 4 |
33730293 | Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression. | 2021 Aug |
5 |
| 5 |
32025610 | Focal Adhesion Kinase Promotes Hepatic Stellate Cell Activation by Regulating Plasma Membrane Localization of TGFβ Receptor 2. | 2020 Feb |
4 |
| 6 |
31171046 | Focal adhesion kinase PTK2 autophosphorylation is not required for the activation of sodium-hydrogen exchange by decreased cell volume in the preimplantation mouse embryo. | 2019 Jun |
1 |
| 7 |
31189647 | Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861. | 2019 Sep 1 |
2 |
| 8 |
31604999 | Small molecule FAK activator promotes human intestinal epithelial monolayer wound closure and mouse ulcer healing. | 2019 Oct 11 |
1 |
| 9 |
29351412 | Expression of CTGF/CCN2 in response to LPA is stimulated by fibrotic extracellular matrix via the integrin/FAK axis. | 2018 Apr 1 |
2 |
| 10 |
30001432 | FAK auto-phosphorylation site tyrosine 397 is required for development but dispensable for normal skin homeostasis. | 2018 |
3 |
| 11 |
28444899 | Focal Adhesion Kinase (FAK) tyrosine 397E mutation restores the vascular leakage defect in endothelium-specific FAK-kinase dead mice. | 2017 Jul |
5 |
| 12 |
28759036 | Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration. | 2017 Nov 23 |
2 |
| 13 |
26886764 | Nanoscale characterization illustrates the cisplatin-mediated biomechanical changes of B16-F10 melanoma cells. | 2016 Mar 14 |
1 |
| 14 |
27009091 | The effects of CEP-37440, an inhibitor of focal adhesion kinase, in vitro and in vivo on inflammatory breast cancer cells. | 2016 Mar 24 |
2 |
| 15 |
27456486 | Pyk2 Controls Integrin-Dependent CTL Migration through Regulation of De-Adhesion. | 2016 Sep 1 |
1 |
| 16 |
26251180 | Focal adhesion kinase phosphorylates the phosphatase and tensin homolog deleted on chromosome 10 under the control of p110δ phosphoinositide-3 kinase. | 2015 Dec |
2 |
| 17 |
26517238 | RNase L is a negative regulator of cell migration. | 2015 Dec 29 |
2 |
| 18 |
24446483 | Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function. | 2014 Jan 20 |
1 |
| 19 |
24755674 | Focal adhesion kinase: an alternative focus for anti-angiogenesis therapy in ovarian cancer. | 2014 Jul |
2 |
| 20 |
25063025 | Plasminogen activator inhibitor-1 regulates infiltration of macrophages into melanoma via phosphorylation of FAK-Tyr⁹²⁵. | 2014 Aug 8 |
2 |
| 21 |
25242698 | Generation of point-mutant FAK knockin mice. | 2014 Nov |
6 |
| 22 |
25319025 | αB-crystallin interacts with and prevents stress-activated proteolysis of focal adhesion kinase by calpain in cardiomyocytes. | 2014 Oct 16 |
2 |
| 23 |
23255596 | Function of focal adhesion kinase scaffolding to mediate endophilin A2 phosphorylation promotes epithelial-mesenchymal transition and mammary cancer stem cell activities in vivo. | 2013 Feb 1 |
1 |
| 24 |
23349702 | SPARC fusion protein induces cellular adhesive signaling. | 2013 |
1 |
| 25 |
23571270 | CB₁ cannabinoid receptors promote maximal FAK catalytic activity by stimulating cooperative signaling between receptor tyrosine kinases and integrins in neuronal cells. | 2013 Aug |
13 |
| 26 |
23637231 | LKB1 represses focal adhesion kinase (FAK) signaling via a FAK-LKB1 complex to regulate FAK site maturation and directional persistence. | 2013 Jun 14 |
3 |
| 27 |
23642017 | Antifibrotic effects of focal adhesion kinase inhibitor in bleomycin-induced pulmonary fibrosis in mice. | 2013 Oct |
1 |
| 28 |
23764511 | β1-Integrin cytoskeletal signaling regulates sensory neuron response to matrix dimensionality. | 2013 Sep 17 |
1 |
| 29 |
23936270 | A role for the protein tyrosine phosphatase CD45 in macrophage adhesion through the regulation of paxillin degradation. | 2013 |
2 |
| 30 |
24055813 | MARVELD1 regulates integrin β1-mediated cell adhesion and actin organization via inhibiting its pre-mRNA processing. | 2013 Nov |
2 |
| 31 |
24108461 | A critical role for Lyn kinase in strengthening endothelial integrity and barrier function. | 2013 Dec 12 |
1 |
| 32 |
24124594 | Sonic hedgehog regulates osteoblast function by focal adhesion kinase signaling in the process of fracture healing. | 2013 |
2 |
| 33 |
22139838 | Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion. | 2012 Jan 20 |
2 |
| 34 |
22320676 | Inhibition of FAK prevents blister formation in the neonatal mouse model of pemphigus vulgaris. | 2012 Apr |
1 |
| 35 |
22366060 | Focal adhesion kinase negatively regulates neuronal insulin resistance. | 2012 Jun |
1 |
| 36 |
22407353 | Targeting focal adhesion assembly by ethoxyfagaronine prevents lymphoblastic cell adhesion to fibronectin. | 2012 |
1 |
| 37 |
22974528 | EBP50 promotes focal adhesion turnover and vascular smooth muscle cells migration. | 2012 Dec |
1 |
| 38 |
23028449 | Focal adhesion kinase plays a role in osteoblast mechanotransduction in vitro but does not affect load-induced bone formation in vivo. | 2012 |
1 |
| 39 |
21289086 | FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusion. | 2011 Apr |
6 |
| 40 |
21876123 | Beta1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation. | 2011 Sep 13 |
2 |
| 41 |
20234191 | PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments. | 2010 May 15 |
2 |
| 42 |
20234193 | Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models. | 2010 May 15 |
3 |
| 43 |
20442405 | Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation. | 2010 Jul 9 |
2 |
| 44 |
20886051 | Suppression of uPAR retards radiation-induced invasion and migration mediated by integrin β1/FAK signaling in medulloblastoma. | 2010 Sep 24 |
1 |
| 45 |
18805968 | Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis. | 2009 Jan 8 |
2 |
| 46 |
19056463 | Abnormal cleavage of APP impairs its functions in cell adhesion and migration. | 2009 Feb 6 |
1 |
| 47 |
19098120 | Quantification of focal adhesion kinase activation loop phosphorylation as a biomarker of Src activity. | 2009 Mar |
3 |
| 48 |
19358301 | FAK silencing inhibits leukemogenesis in BCR/ABL-transformed hematopoietic cells. | 2009 May |
2 |
| 49 |
19501627 | PTEN and SHIP2 regulates PI3K/Akt pathway through focal adhesion kinase. | 2009 Oct 15 |
1 |
| 50 |
19628583 | A preformed signaling complex mediates GnRH-activated ERK phosphorylation of paxillin and FAK at focal adhesions in L beta T2 gonadotrope cells. | 2009 Nov |
1 |