Tyrosine

PTK2 protein tyrosine kinase 2 ; Mus musculus







183 Article(s)
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51 19776009 Autophosphorylation-independent and -dependent functions of focal adhesion kinase during development. 2009 Dec 11 1
52 17914455 Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo. 2008 Mar 1
53 17922492 A FAK/Src chimera with gain-of-function properties promotes formation of large peripheral adhesions associated with dynamic actin assembly. 2008 Jan 2
54 18195107 PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility. 2008 Jan 14 1
55 18233957 Functional analysis of Src homology 3-encoding exon (exon 2) of p130Cas in primary fibroblasts derived from exon 2-specific knockout mice. 2008 Feb 1
56 18356303 Deficiency in the LIM-only protein FHL2 impairs assembly of extracellular matrix proteins. 2008 Jul 1
57 18505823 The headpiece domain of dematin regulates cell shape, motility, and wound healing by modulating RhoA activation. 2008 Aug 1
58 18523140 Effects of active and inactive phospholipase D2 on signal transduction, adhesion, migration, invasion, and metastasis in EL4 lymphoma cells. 2008 Sep 2
59 18793427 Phosphorylation of p130Cas initiates Rac activation and membrane ruffling. 2008 Sep 15 1
60 17289681 Preferential phosphorylation of focal adhesion kinase tyrosine 861 is critical for mediating an anti-apoptotic response to hyperosmotic stress. 2007 Apr 6 9
61 17303567 Focal adhesion kinase is negatively regulated by phosphorylation at tyrosine 407. 2007 Apr 6 14
62 17333113 Focal adhesion kinase regulates insulin resistance in skeletal muscle. 2007 May 1
63 17526730 Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment. 2007 Aug 1
64 17976369 Phosphorylation of focal adhesion kinase at Tyrosine 407 negatively regulates Ras transformation of fibroblasts. 2007 Dec 28 9
65 16293639 Activation of the lutropin/choriogonadotropin receptor in MA-10 cells leads to the tyrosine phosphorylation of the focal adhesion kinase by a pathway that involves Src family kinases. 2006 Mar 4
66 16374517 Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice. 2006 Jan 1
67 16508962 Adhesion and proliferation of fibroblasts on RF plasma-deposited nanostructured fluorocarbon coatings: evidence of FAK activation. 2006 Jun 1
68 16972260 Homocysteine-induced myofibroblast differentiation in mouse aortic endothelial cells. 2006 Dec 2
69 15761030 (alpha)v(beta)3 integrins and Pyk2 mediate insulin-like growth factor I activation of Src and mitogen-activated protein kinase in 3T3-L1 cells. 2005 Jul 2
70 15842360 SHPS-1 negatively regulates integrin alphaIIbbeta3 function through CD47 without disturbing FAK phosphorylation. 2005 Apr 1
71 15845548 G protein-coupled receptor activation rapidly stimulates focal adhesion kinase phosphorylation at Ser-843. Mediation by Ca2+, calmodulin, and Ca2+/calmodulin-dependent kinase II. 2005 Jun 24 2
72 16132110 Differential effect of the focal adhesion kinase Y397F mutant on v-Src-stimulated cell invasion and tumor growth. 2005 2
73 16388318 Ligand-mimetic anti-alphaIIb beta3 antibody PAC-1 inhibits tyrosine signaling, proliferation and lung colonization of melanoma cells. 2005 1
74 14966364 Attenuation of mouse mesangial cell contractility by high glucose and mannitol: involvement of protein kinase C and focal adhesion kinase. 2004 Mar-Apr 1
75 15034138 The integrin beta1 subunit transmembrane domain regulates phosphatidylinositol 3-kinase-dependent tyrosine phosphorylation of Crk-associated substrate. 2004 Jun 2
76 15123632 Phosphorylation of focal adhesion kinase at tyrosine 861 is crucial for Ras transformation of fibroblasts. 2004 Jul 9 10
77 15132756 Recruitment of focal adhesion kinase and paxillin to beta1 integrin promotes cancer cell migration via mitogen activated protein kinase activation. 2004 May 7 2
78 15174091 PDGF and FGF induce focal adhesion kinase (FAK) phosphorylation at Ser-910: dissociation from Tyr-397 phosphorylation and requirement for ERK activation. 2004 Aug 6
79 15302877 Hyperosmotic stress induces rapid focal adhesion kinase phosphorylation at tyrosines 397 and 577. Role of Src family kinases and Rho family GTPases. 2004 Oct 22 10
80 15554394 Protein phosphatase-2A maintains focal adhesion complexes in keratinocytes and the loss of this regulation in squamous cell carcinomas. 2004 1
81 12466150 Tumor necrosis factor regulates intestinal epithelial cell migration by receptor-dependent mechanisms. 2003 Apr 3
82 12515828 PTP alpha regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migration. 2003 Jan 6 3
83 12548551 Dissociation of focal adhesion kinase and paxillin tyrosine phosphorylation induced by bombesin and lysophosphatidic acid from epidermal growth factor receptor transactivation in Swiss 3T3 cells. 2003 Mar 4
84 12551902 Signaling between focal adhesion kinase and trio. 2003 Apr 11 4
85 12692126 Bombesin, lysophosphatidic acid, and epidermal growth factor rapidly stimulate focal adhesion kinase phosphorylation at Ser-910: requirement for ERK activation. 2003 Jun 20 1
86 12702722 Direct interaction of focal adhesion kinase with p190RhoGEF. 2003 Jul 4 5
87 14529092 Binding of alpha5 monoclonal antibody to cell surface alpha5beta1 integrin modulates MMP-2 and MMP-7 activity in B16F10 melanoma cells. 2003 2
88 14634134 Alterations in granule matrix and cell surface of focal adhesion kinase-deficient mast cells. 2003 Dec 1 2
89 11784715 Hepatocyte growth factor induces ERK-dependent paxillin phosphorylation and regulates paxillin-focal adhesion kinase association. 2002 Mar 22 2
90 11791180 Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase. 2002 Jan 3 2
91 11821402 Trichostatin A-induced detransformation correlates with decreased focal adhesion kinase phosphorylation at tyrosine 861 in ras-transformed fibroblasts. 2002 Apr 12 7
92 11927607 Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling. 2002 Apr 1 2
93 11980671 Focal adhesion kinase enhances signaling through the Shc/extracellular signal-regulated kinase pathway in anaplastic astrocytoma tumor biopsy samples. 2002 May 1 1
94 12027949 Focal adhesion kinase tyrosine phosphorylation is associated with myogenesis and modulated by insulin. 2002 Jun 3
95 12083484 FAK-mediated inhibition of vascular smooth muscle cell migration by the tetraspanin CD9. 2002 Jun 2
96 12083796 Mitogen-induced, FAK-dependent tyrosine phosphorylation of the SSeCKS scaffolding protein. 2002 Jul 15 3
97 12087088 Syndecan-4 modulates focal adhesion kinase phosphorylation. 2002 Sep 6 4
98 12091389 Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1. 2002 Sep 13 1
99 12114453 A new type of antimetastatic peptide derived from fibronectin. 2002 Jul 2
100 12163181 CB1 cannabinoid receptor-mediated tyrosine phosphorylation of focal adhesion kinase-related non-kinase. 2002 Aug 14 8