Title : Quantification of focal adhesion kinase activation loop phosphorylation as a biomarker of Src activity.

Pub. Date : 2009 Mar

PMID : 19098120






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This revealed that bis-phosphorylated pTyr(576)/Tyr(577)-FAK was a biomarker of Src activity and inactivation in vitro and in cell culture. Tyrosine PTK2 protein tyrosine kinase 2 Mus musculus
2 Phosphorylation of FAK at Tyr(576)/Tyr(577) was inhibited by AZD0530 in a dose-dependent manner both in cell culture and in vitro. Tyrosine PTK2 protein tyrosine kinase 2 Mus musculus
3 Phosphorylation of FAK at Tyr(576)/Tyr(577) was inhibited by AZD0530 in a dose-dependent manner both in cell culture and in vitro. Tyrosine PTK2 protein tyrosine kinase 2 Mus musculus