Tyrosine

Rac family small GTPase 1 ; Homo sapiens







41 Article(s)
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1 32823607 Enforced C-Src Activation Causes Compartmental Dysregulation of PI3K and PTEN Molecules in Lipid Rafts of Tongue Squamous Carcinoma Cells by Attenuating Rac1-Akt-GLUT-1-Mediated Sphingolipid Synthesis. 2020 Aug 13 1
2 31644919 Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation. 2019 Oct 22 1
3 28073159 Polymeric immunoglobulin receptor promotes tumor growth in hepatocellular carcinoma. 2017 Jun 1
4 26752742 Tyrosine 397 phosphorylation is critical for FAK-promoted Rac1 activation and invasive properties in oral squamous cell carcinoma cells. 2016 Mar 1
5 27519475 Lck/PLCγ control migration and proliferation of interleukin (IL)-2-stimulated T cells via the Rac1 GTPase/glycogen phosphorylase pathway. 2016 Nov 1
6 27562306 Tyrosine 397 phosphorylation is critical for FAK-promoted Rac1 activation and invasive properties in oral squamous cell carcinoma cells. 2016 Sep 1
7 27562307 Response to: Tyrosine 397 phosphorylation is critical for FAK-promoted Rac1 activation and invasive properties in oral squamous cell carcinoma cells. 2016 Sep 1
8 24025335 Novel role for p21-activated kinase 2 in thrombin-induced monocyte migration. 2013 Oct 25 1
9 22659453 Vav3-rac1 signaling regulates prostate cancer metastasis with elevated Vav3 expression correlating with prostate cancer progression and posttreatment recurrence. 2012 Jun 15 1
10 21619876 The R(h)oads to Stat3: Stat3 activation by the Rho GTPases. 2011 Aug 1 1
11 22080864 Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans. 2011 Dec 1
12 22163037 Tyrosine phosphorylation of Rac1: a role in regulation of cell spreading. 2011 1
13 19404567 How increased VEGF induces glomerular hyperpermeability: a potential signaling pathway of Rac1 activation. 2010 Dec 1
14 19366706 Phospholipase D-mediated activation of IQGAP1 through Rac1 regulates hyperoxia-induced p47phox translocation and reactive oxygen species generation in lung endothelial cells. 2009 May 29 2
15 18172037 Angiotensin II activates signal transducer and activators of transcription 3 via Rac1 in atrial myocytes and fibroblasts: implication for the therapeutic effect of statin in atrial structural remodeling. 2008 Jan 22 2
16 18459146 Selective amino acid restriction differentially affects the motility and directionality of DU145 and PC3 prostate cancer cells. 2008 Oct 1
17 17088251 Repetitive deformation activates focal adhesion kinase and ERK mitogenic signals in human Caco-2 intestinal epithelial cells through Src and Rac1. 2007 Jan 5 1
18 17093062 FAK potentiates Rac1 activation and localization to matrix adhesion sites: a role for betaPIX. 2007 Jan 2
19 17560670 Tyrosine phosphorylation of beta2-chimaerin by Src-family kinase negatively regulates its Rac-specific GAP activity. 2007 Sep 1
20 17686471 VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2. 2007 Sep 10 1
21 17786281 Src regulates phorbol 12-myristate 13-acetate-activated PKC-induced migration via Cas/Crk/Rac1 signaling pathway in glioblastoma cells. 2007 Oct 1
22 17854274 MKK6 phosphorylation regulates production of superoxide by enhancing Rac GTPase activity. 2007 Nov 2
23 15485841 Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src- and Cdc42-mediated activation of Rac. 2005 Feb 11 1
24 15673687 A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells. 2005 Feb 1 1
25 15778498 Proline-rich tyrosine kinase 2 (Pyk2) mediates vascular endothelial-cadherin-based cell-cell adhesion by regulating beta-catenin tyrosine phosphorylation. 2005 Jun 3 1
26 15893190 The tyrosine phosphatase, SHP-1, is a negative regulator of endothelial superoxide formation. 2005 May 17 1
27 15976327 Caveolin-1 is essential for activation of Rac1 and NAD(P)H oxidase after angiotensin II type 1 receptor stimulation in vascular smooth muscle cells: role in redox signaling and vascular hypertrophy. 2005 Sep 1
28 12556491 Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors. 2003 Feb 2
29 12810717 Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src. 2003 Sep 5 1
30 12925758 Cortactin tyrosine phosphorylation requires Rac1 activity and association with the cortical actin cytoskeleton. 2003 Aug 5
31 12215529 Cdc42/Rac1-mediated activation primes PAK2 for superactivation by tyrosine phosphorylation. 2002 Oct 1
32 11595749 Trp(56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factors. 2001 Dec 14 2
33 11781818 How Vav proteins discriminate the GTPases Rac1 and RhoA from Cdc42. 2001 Dec 6 1
34 10882715 Stimulation of Ras guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) upon tyrosine phosphorylation by the Cdc42-regulated kinase ACK1. 2000 Sep 22 1
35 10900195 Cdc42Hs and Rac1 GTPases induce the collapse of the vimentin intermediate filament network. 2000 Oct 20 1
36 11021801 Regulation of STAT3 by direct binding to the Rac1 GTPase. 2000 Oct 6 1
37 11034388 CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation. 2000 Oct 1 1
38 9488489 Signaling through CD5 activates a pathway involving phosphatidylinositol 3-kinase, Vav, and Rac1 in human mature T lymphocytes. 1998 Mar 2
39 9488731 Vav binding to heterogeneous nuclear ribonucleoprotein (hnRNP) C. Evidence for Vav-hnRNP interactions in an RNA-dependent manner. 1998 Mar 6 1
40 8990121 Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product. 1997 Jan 9 2
41 9109498 The VAV family of signal transduction molecules. 1996 1