Title : Vav3-rac1 signaling regulates prostate cancer metastasis with elevated Vav3 expression correlating with prostate cancer progression and posttreatment recurrence.

Pub. Date : 2012 Jun 15

PMID : 22659453






1 Functional Relationships(s)
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Protein Name
Organism
1 Stimulation of the receptor tyrosine kinase EphA2 by ephrinA1 resulted in recruitment and tyrosine phosphorylation of Vav3, leading to Rac1 activation as well as increased migration and invasion in vitro. Tyrosine Rac family small GTPase 1 Homo sapiens