Title : FAK potentiates Rac1 activation and localization to matrix adhesion sites: a role for betaPIX.

Pub. Date : 2007 Jan

PMID : 17093062






2 Functional Relationships(s)
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1 We demonstrated that FAK tyrosine-phosphorylated betaPIX and thereby increased its binding to Rac1. Tyrosine Rac family small GTPase 1 Homo sapiens
2 These data indicate that FAK has a role in the activation and focal adhesion translocation of Rac1 through the tyrosine phosphorylation of betaPIX. Tyrosine Rac family small GTPase 1 Homo sapiens