Calcium

myosin heavy chain 14 ; Homo sapiens







230 Article(s)
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1 34859613 Facioscapulohumeral dystrophy weakened sarcomeric contractility is mimicked in induced pluripotent stem cells-derived innervated muscle fibres. 2022 Feb 1
2 34942531 The effects of the tropomyosin cardiomyopathy mutations on the calcium regulation of actin-myosin interaction in the atrium and ventricle differ. 2022 Jan 15 2
3 35150133 DDR1 associates with TRPV4 in cell-matrix adhesions to enable calcium-regulated myosin activity and collagen compaction. 2022 May 1
4 35563042 Identification of Potential Muscle Biomarkers in McArdle Disease: Insights from Muscle Proteome Analysis. 2022 Apr 22 1
5 33416833 Dependence of thick filament structure in relaxed mammalian skeletal muscle on temperature and interfilament spacing. 2021 Mar 1 1
6 33850019 Stress-dependent activation of myosin in the heart requires thin filament activation and thick filament mechanosensing. 2021 Apr 20 4
7 34161147 A troponin T variant linked with pediatric dilated cardiomyopathy reduces the coupling of thin filament activation to myosin and calcium binding. 2021 Aug 19 1
8 34357074 Characterization of Contractile Machinery of Vascular Smooth Muscles in Hypertension. 2021 Jul 16 1
9 34508779 Velocity of myosin-based actin sliding depends on attachment and detachment kinetics and reaches a maximum when myosin-binding sites on actin saturate. 2021 Nov 1
10 34569933 Single-molecule imaging reveals the concerted release of myosin from regulated thin filaments. 2021 Sep 27 1
11 34668926 Myosin motors that cannot bind actin leave their folded OFF state on activation of skeletal muscle. 2021 Nov 1 1
12 31864708 The molecular mechanism of muscle dysfunction associated with the R133W mutation in Tpm2.2. 2020 Feb 26 3
13 31983430 18O labeling on Ser45 but not on Ser35 supports the cooperative phosphorylation mechanism on tarantula thick filament activation. 2020 Mar 26 1
14 32098556 Variant R94C in TNNT2-Encoded Troponin T Predisposes to Pediatric Restrictive Cardiomyopathy and Sudden Death Through Impaired Thin Filament Relaxation Resulting in Myocardial Diastolic Dysfunction. 2020 Mar 3 1
15 32444484 The myosin interacting-heads motif present in live tarantula muscle explains tetanic and posttetanic phosphorylation mechanisms. 2020 Jun 2 1
16 32840354 Eliminating the First Inactive State and Stabilizing the Active State of the Cardiac Regulatory System Alters Behavior in Solution and in Ordered Systems. 2020 Sep 22 1
17 30877248 Revealing the mechanism of how cardiac myosin-binding protein C N-terminal fragments sensitize thin filaments for myosin binding. 2019 Apr 2 1
18 31177460 Effect of Interchain Disulfide Crosslinking in the Tropomyosin Molecule on Actin-Myosin Interaction in the Atrial Myocardium. 2019 May 1
19 31556008 CaATP prolongs strong actomyosin binding and promotes futile myosin stroke. 2019 Dec 2
20 29052230 Omecamtiv mercabil and blebbistatin modulate cardiac contractility by perturbing the regulatory state of the myosin filament. 2018 Jan 1 1
21 29394331 Vascular smooth muscle contraction in hypertension. 2018 Mar 15 1
22 29671777 Calcium and Nuclear Signaling in Prostate Cancer. 2018 Apr 19 2
23 29707029 Cardiac myosin activators for heart failure therapy: focus on omecamtiv mecarbil. 2018 1
24 29738686 The Effect of Experimental Hyperthyroidism on Characteristics of Actin-Myosin Interaction in Fast and Slow Skeletal Muscles. 2018 May 1
25 30266320 Thick-Filament Extensibility in Intact Skeletal Muscle. 2018 Oct 16 2
26 30346792 Nanothermometry Reveals Calcium-Induced Remodeling of Myosin. 2018 Nov 14 5
27 27956182 Phosphorylation of proteins during human myometrial contractions: A phosphoproteomic approach. 2017 Jan 22 1
28 28082673 Omecamtiv Mecarbil Enhances the Duty Ratio of Human β-Cardiac Myosin Resulting in Increased Calcium Sensitivity and Slowed Force Development in Cardiac Muscle. 2017 Mar 3 2
29 28176871 The earliest molecular response to stretch of insect flight muscle as revealed by fast X-ray diffraction recording. 2017 Feb 8 1
30 28315072 Direct Myosin Activation by Omecamtiv Mecarbil for Heart Failure with Reduced Ejection Fraction. 2017 1
31 28623140 The isoforms of α-actin and myosin affect the Ca2+ regulation of the actin-myosin interaction in the heart. 2017 Aug 19 3
32 29262355 Regulation of Contraction by the Thick Filaments in Skeletal Muscle. 2017 Dec 19 1
33 26908872 Phosphorylation and calcium antagonistically tune myosin-binding protein C's structure and function. 2016 Mar 22 2
34 27192697 Calcium-regulated import of myosin IC into the nucleus. 2016 Jun 1
35 27395017 Order-Disorder Transitions in the Cardiac Troponin Complex. 2016 Jul 31 1
36 27421960 Prothrombotic skeletal muscle myosin directly enhances prothrombin activation by binding factors Xa and Va. 2016 Oct 6 1
37 27434086 Muscle Fatigue from the Perspective of a Single Crossbridge. 2016 Nov 1
38 27796302 Thick filament mechano-sensing is a calcium-independent regulatory mechanism in skeletal muscle. 2016 Oct 31 1
39 27878731 Effect of Cardiomyopathic Mutations in Tropomyosin on Calcium Regulation of the Actin-Myosin Interaction in Skeletal Muscle. 2016 Nov 3
40 25429108 Using fluorescent myosin to directly visualize cooperative activation of thin filaments. 2015 Jan 23 1
41 26116101 Why the heart is like an orchestra and the uterus is like a soccer crowd. 2015 Aug 1
42 26262582 A Spatially Detailed Model of Isometric Contraction Based on Competitive Binding of Troponin I Explains Cooperative Interactions between Tropomyosin and Crossbridges. 2015 Aug 1
43 26333401 Actin filaments as the fast pathways for calcium ions involved in auditory processes. 2015 Sep 1
44 26536123 Direct Measurements of Local Coupling between Myosin Molecules Are Consistent with a Model of Muscle Activation. 2015 Nov 1
45 26878579 Investigations of Molecular Mechanisms of Actin-Myosin Interactions in Cardiac Muscle. 2015 Dec 2
46 24066930 Commentary on the special issue on the impact of myogenic tone in health and disease. 2014 2
47 24989796 Calcium-dependent phosphorylation alters class XIVa myosin function in the protozoan parasite Toxoplasma gondii. 2014 Sep 1 3
48 25392916 Ca2+-induced PRE-NMR changes in the troponin complex reveal the possessive nature of the cardiac isoform for its regulatory switch. 2014 1
49 25400587 O-GlcNAcylation, contractile protein modifications and calcium affinity in skeletal muscle. 2014 2
50 23554884 Calcium induced regulation of skeletal troponin--computational insights from molecular dynamics simulations. 2013 1