Title : Effect of Cardiomyopathic Mutations in Tropomyosin on Calcium Regulation of the Actin-Myosin Interaction in Skeletal Muscle.

Pub. Date : 2016 Nov

PMID : 27878731






3 Functional Relationships(s)
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1 Effect of Cardiomyopathic Mutations in Tropomyosin on Calcium Regulation of the Actin-Myosin Interaction in Skeletal Muscle. Calcium myosin heavy chain 14 Homo sapiens
2 We studied the effect of mutations in the alpha-chain of tropomyosin related to hypertrophic (D175N and E180G) and dilated cardiomyopathies (E40K and E54K) on calcium regulation of the actin-myosin interaction in skeletal muscles. Calcium myosin heavy chain 14 Homo sapiens
3 We analyzed the calcium-dependent sliding velocity of reconstructed thin filaments containing F-actin, troponin, and tropomyosin over myosin surface in an in vitro motility assay. Calcium myosin heavy chain 14 Homo sapiens