Title : Omecamtiv mercabil and blebbistatin modulate cardiac contractility by perturbing the regulatory state of the myosin filament.

Pub. Date : 2018 Jan 1

PMID : 29052230






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 ABSTRACT: Contraction of heart muscle is triggered by a transient rise in intracellular free calcium concentration linked to a change in the structure of the actin-containing thin filaments that allows the head or motor domains of myosin from the thick filaments to bind to them and induce filament sliding. Calcium myosin heavy chain 14 Homo sapiens