Pub. Date : 2016 Mar 22
PMID : 26908872
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | During each heartbeat, cardiac contractility results from calcium-activated sliding of actin thin filaments toward the centers of myosin thick filaments to shorten cellular length. | Calcium | myosin heavy chain 14 | Homo sapiens |
| 2 | Cardiac myosin-binding protein C (cMyBP-C) is a component of the thick filament that appears to tune these mechanochemical interactions by its N-terminal domains transiently interacting with actin and/or the myosin S2 domain, sensitizing thin filaments to calcium and governing maximal sliding velocity. | Calcium | myosin heavy chain 14 | Homo sapiens |