monorden

heat shock protein 90 alpha family class A member 1 ; Homo sapiens







150 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35569376 Regulation of SLC6A14 trafficking in breast cancer cells by heat shock protein HSP90β. 2022 Jul 23 1
2 33802597 Identification of Predictive Biomarkers of Response to HSP90 Inhibitors in Lung Adenocarcinoma. 2021 Mar 3 1
3 33903104 Radicicol Inhibits Chikungunya Virus Replication by Targeting Nonstructural Protein 2. 2021 Jun 17 1
4 34221862 The disruption of protein-protein interactions with co-chaperones and client substrates as a strategy towards Hsp90 inhibition. 2021 Jun 2
5 34262899 NudC L279P Mutation Destabilizes Filamin A by Inhibiting the Hsp90 Chaperoning Pathway and Suppresses Cell Migration. 2021 1
6 32295059 Understanding the Hsp90 N-terminal Dynamics: Structural and Molecular Insights into the Therapeutic Activities of Anticancer Inhibitors Radicicol (RD) and Radicicol Derivative (NVP-YUA922). 2020 Apr 13 3
7 32497199 Heat shock protein 90 inhibitors suppress pyroptosis in THP-1 cells. 2020 Oct 30 1
8 33077554 Nanoengineered Disruption of Heat Shock Protein 90 Targets Drug-Induced Resistance and Relieves Natural Killer Cell Suppression in Breast Cancer. 2020 Dec 1 1
9 31326539 Amino acid transporter SLC6A14 depends on heat shock protein HSP90 in trafficking to the cell surface. 2019 Oct 1
10 28641528 Drug Design, Synthesis and In Vitro Evaluation of Substituted Benzofurans as Hsp90 Inhibitors. 2018 1
11 29677383 Effects of Inhibitors on Hsp90's Conformational Dynamics, Cochaperone and Client Interactions. 2018 Jul 17 1
12 30483129 Combined Pharmacological Inhibition of Cyclophilins, FK506-Binding Proteins, Hsp90, and Hsp70 Protects Cells From Clostridium botulinum C2 Toxin. 2018 1
13 32231947 Deoxynivalenol and Nivalenol Toxicities in Cultured Cells: a Review of Comparative Studies. 2018 Jun 1
14 28306192 Histone deacetylase activity mediates acquired resistance towards structurally diverse HSP90 inhibitors. 2017 May 1
15 28758577 Translational Shift of HSP90 as a Novel Therapeutic Target from Cancer to Neurodegenerative Disorders: An Emerging Trend in the Cure of Alzheimer's and Parkinson's Diseases. 2017 1
16 28779264 Hyponatremia and V2 vasopressin receptor upregulation: a result of HSP90 inhibition. 2017 Oct 1
17 27059856 The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain. 2016 Jun 15 1
18 27205876 Key role of heat shock protein 90 in leptin-induced STAT3 activation and feeding regulation. 2016 Aug 1
19 27233944 Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity. 2016 Aug 1
20 27563925 Reduced Contractility and Motility of Prostatic Cancer-Associated Fibroblasts after Inhibition of Heat Shock Protein 90. 2016 Aug 24 1
21 25680466 Radicicol induces intracellular accumulation of glycan-deficient clusterin variant. 2015 Mar 13 1
22 25957766 Induction of heat shock protein HSPA6 (HSP70B') upon HSP90 inhibition in cancer cell lines. 2015 Jun 4 1
23 26475763 Potential role of vitexin in alleviating heat stress-induced cytotoxicity: Regulatory effect of Hsp90 on ER stress-mediated autophagy. 2015 Dec 1 1
24 25202064 Hsp70 inhibition potentiates radicicol-induced cell death in anaplastic thyroid carcinoma cells. 2014 Sep 2
25 22920907 Hsp90 inhibitors as anti-cancer agents, from basic discoveries to clinical development. 2013 2
26 23107115 The Hsp90-Sti1 interaction is critical for Leishmania donovani proliferation in both life cycle stages. 2013 Apr 1
27 23114515 Low endogenous and chemical induced heat shock protein induction in a 0N3Rtau-expressing Drosophila larval model of Alzheimer's disease. 2013 1
28 23496136 Learning from nature: advances in geldanamycin- and radicicol-based inhibitors of Hsp90. 2013 Jun 7 1
29 23727383 Radicicol, a heat shock protein 90 inhibitor, inhibits differentiation and adipogenesis in 3T3-L1 preadipocytes. 2013 Jun 28 1
30 23763277 The anticancer drug AUY922 generates a proteomics fingerprint that is highly conserved among structurally diverse Hsp90 inhibitors. 2013 Aug 2 1
31 21465483 Regulation of endothelial barrier function by TGF-β type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90. 2012 Feb 2
32 21800052 Radicicol, an inhibitor of Hsp90, enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells by promoting activation of apoptosis-related proteins. 2012 Jan 1
33 22215907 Hsp90 molecular chaperone inhibitors: are we there yet? 2012 Jan 1 1
34 22496241 Hsp90 regulates O-linked β-N-acetylglucosamine transferase: a novel mechanism of modulation of protein O-linked β-N-acetylglucosamine modification in endothelial cells. 2012 Jun 15 1
35 23350198 [Thermosensitization of tumor cells with inhibitors of chaperone activity and expression]. 2012 Nov-Dec 3
36 24280675 Heat shock protein 90 and role of its chemical inhibitors in treatment of hematologic malignancies. 2012 Jul 25 2
37 21145921 Modulation of α(2C) adrenergic receptor temperature-sensitive trafficking by HSP90. 2011 Feb 1
38 21357526 Hsp90 interacts with inducible NO synthase client protein in its heme-free state and then drives heme insertion by an ATP-dependent process. 2011 Jun 1
39 21368131 Benzoquinone ansamycin 17AAG binds to mitochondrial voltage-dependent anion channel and inhibits cell invasion. 2011 Mar 8 1
40 21439943 Hsp90 is involved in the formation of P-bodies and stress granules. 2011 Apr 22 1
41 21932796 Targeting the Hsp90 molecular chaperone with novel macrolactams. Synthesis, structural, binding, and cellular studies. 2011 Dec 16 2
42 19408974 Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells. 2010 Jan 1
43 19948165 Protection of oligodendrocyte precursor cells by low doses of HSP90 inhibitors in cell culture. 2010 Sep 4
44 20138026 A simple yeast-based system for analyzing inhibitor resistance in the human cancer drug targets Hsp90alpha/beta. 2010 Jun 1 1
45 20534344 Application of proteomic profiling based on 2D-DIGE for classification of compounds according to the mechanism of action. 2010 May 28 2
46 20552022 Induction of premature senescence by hsp90 inhibition in small cell lung cancer. 2010 Jun 11 1
47 20943306 Thermodynamics of radicicol binding to human Hsp90 alpha and beta isoforms. 2010 Nov 4
48 18726712 Heat shock protein 90 is involved in regulation of hypoxia-driven proliferation of embryonic neural stem/progenitor cells. 2009 Mar 1
49 19136580 Heat shock protein 90-eNOS interactions mature with postnatal age in the pulmonary circulation of the piglet. 2009 Mar 1
50 19162015 High cytotoxic sensitivity of the oligodendrocyte precursor cells to HSP90 inhibitors in cell cultures. 2009 Apr 1