Title : Hsp90 regulates O-linked β-N-acetylglucosamine transferase: a novel mechanism of modulation of protein O-linked β-N-acetylglucosamine modification in endothelial cells.

Pub. Date : 2012 Jun 15

PMID : 22496241






1 Functional Relationships(s)
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1 Inhibition of Hsp90 by its specific inhibitors, radicicol or 17-N-allylamino-17-demethoxygeldanamycin, destabilized OGT in primary endothelial cell cultures and enhanced its degradation by the proteasome. monorden heat shock protein 90 alpha family class A member 1 Homo sapiens