Title : Induction of premature senescence by hsp90 inhibition in small cell lung cancer.

Pub. Date : 2010 Jun 11

PMID : 20552022






1 Functional Relationships(s)
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1 METHODOLOGY/PRINCIPAL FINDINGS: In MTT assays, small cell lung cancer cells showed a biphasic response to the Hsp90 inhibitors geldanamycin and radicicol, with low concentrations causing proliferation arrest and high concentrations causing cell death. monorden heat shock protein 90 alpha family class A member 1 Homo sapiens