Title : CHRNA5 variants moderate the effect of nicotine deprivation on a neural index of cognitive control.

Pub. Date : 2014 Sep

PMID : 24934182






3 Functional Relationships(s)
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1 CHRNA5 variants moderate the effect of nicotine deprivation on a neural index of cognitive control. Nicotine cholinergic receptor nicotinic alpha 5 subunit Homo sapiens
2 Minor allele carriers at rs16969968 in the nicotinic acetylcholine receptor alpha5 subunit gene (CHRNA5) have been shown to exhibit both reduced cognitive control and greater nicotine dependence. Nicotine cholinergic receptor nicotinic alpha 5 subunit Homo sapiens
3 We tested the hypothesis that individuals possessing at least one minor allele at rs16969968 in CHRNA5 would show greater nicotine deprivation-induced reductions in P3b and P3a amplitude. Nicotine cholinergic receptor nicotinic alpha 5 subunit Homo sapiens