Pub. Date : 2016 May
PMID : 26239294
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans. | Nicotine | cholinergic receptor nicotinic alpha 5 subunit | Homo sapiens |
2 | The common nonsynonymous variant rs16969968 in the alpha5 nicotinic receptor subunit gene (CHRNA5) is the strongest genetic risk factor for nicotine dependence in European Americans and contributes to risk in African Americans. | Nicotine | cholinergic receptor nicotinic alpha 5 subunit | Homo sapiens |
3 | Our results indicate that common, low frequency and rare CHRNA5 coding variants are independently associated with nicotine dependence risk. | Nicotine | cholinergic receptor nicotinic alpha 5 subunit | Homo sapiens |