Title : Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans.

Pub. Date : 2016 May

PMID : 26239294






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans. Nicotine cholinergic receptor nicotinic alpha 5 subunit Homo sapiens
2 The common nonsynonymous variant rs16969968 in the alpha5 nicotinic receptor subunit gene (CHRNA5) is the strongest genetic risk factor for nicotine dependence in European Americans and contributes to risk in African Americans. Nicotine cholinergic receptor nicotinic alpha 5 subunit Homo sapiens
3 Our results indicate that common, low frequency and rare CHRNA5 coding variants are independently associated with nicotine dependence risk. Nicotine cholinergic receptor nicotinic alpha 5 subunit Homo sapiens