Nicotine

cholinergic receptor nicotinic alpha 5 subunit ; Homo sapiens







91 Article(s)
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51 22008662 The association of the alpha-5 subunit of the nicotinic acetylcholine receptor gene and the brain-derived neurotrophic factor gene with different aspects of smoking behavior. 2012 Apr 2
52 22012472 Childhood adversity increases risk for nicotine dependence and interacts with α5 nicotinic acetylcholine receptor genotype specifically in males. 2012 Feb 1
53 22042234 Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster. 2012 May 1
54 22042774 Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence. 2012 Feb 1 1
55 22101982 Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects. 2012 Aug 1
56 22102629 Dissection of the phenotypic and genotypic associations with nicotinic dependence. 2012 Apr 1
57 22241830 Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits. 2012 Jun 1
58 22380605 Subunit composition of α5-containing nicotinic receptors in the rodent habenula. 2012 May 1
59 22640768 The genetic basis of addictive disorders. 2012 Jun 1
60 22820273 Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by α3β4α5 nicotinic acetylcholine receptors. 2012 Nov 1
61 23061658 Role of CHRNA5-A3 genetic Locus variants and developing drug for chronic obstructive pulmonary disease. 2012 1
62 20700147 Nicotinic α5 receptor subunit mRNA expression is associated with distant 5' upstream polymorphisms. 2011 Jan 1
63 21048701 Partial agonists of the α3β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats. 2011 Feb 1
64 21228559 An exploratory study on the CHRNA3-CHRNA5-CHRNB4 cluster, smoking, and Parkinson's disease. 2011 1
65 21268243 Markers in the 15q24 nicotinic receptor subunit gene cluster (CHRNA5-A3-B4) predict severity of nicotine addiction and response to smoking cessation therapy. 2011 Apr 2
66 21418140 A CHRNA5 allele related to nicotine addiction and schizophrenia. 2011 Jul 1
67 21586512 CHRNA5 as negative regulator of nicotine signaling in normal and cancer bronchial cells: effects on motility, migration and p63 expression. 2011 Sep 1
68 21747048 Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk. 2011 Sep 7 2
69 21858091 In vitro and ex vivo analysis of CHRNA3 and CHRNA5 haplotype expression. 2011 1
70 22028403 A case-control study of a sex-specific association between a 15q25 variant and lung cancer risk. 2011 Dec 1
71 22046326 'Smoking genes': a genetic association study. 2011 1
72 22071378 Association of the CHRNA5-A3-B4 gene cluster with heaviness of smoking: a meta-analysis. 2011 Dec 1
73 19859904 Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans. 2010 Apr 5 3
74 20124469 ASCL1 regulates the expression of the CHRNA5/A3/B4 lung cancer susceptibility locus. 2010 Feb 1
75 20564069 Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5-A3 genetic locus and lung cancer risk. 2010 Jul 15 1
76 20685379 The nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster: dual role in nicotine addiction and lung cancer. 2010 Oct 1
77 20700436 Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. 2010 Aug 5 1
78 20808433 Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population. 2010 Aug 16 2
79 20840187 Peer smoking and the nicotinic receptor genes: an examination of genetic and environmental risks for nicotine dependence. 2010 Nov 2
80 19436041 Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes. 2009 Jul 2
81 19443489 Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. 2009 Aug 15 6
82 19628476 Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15. 2009 Oct 15 3
83 19641473 Racial differences in the association between SNPs on 15q25.1, smoking behavior, and risk of non-small cell lung cancer. 2009 Oct 1
84 19706762 The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. 2009 Sep 1 4
85 20871796 Interplay of Genetic Risk Factors and Parent Monitoring in Risk for Nicotine Dependence. 2009 Oct 1
86 18519132 A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence. 2008 Dec 1 3
87 18519524 Variants in nicotinic receptors and risk for nicotine dependence. 2008 Sep 1
88 18618000 A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction. 2008 Jul 11 3
89 18783506 Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking. 2008 Sep 2
90 18957677 The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer. 2008 Nov 5 1
91 19064933 Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans. 2008 Dec 23 1