Guanosine Triphosphate

Raf-1 proto-oncogene, serine/threonine kinase ; Homo sapiens







40 Article(s)
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Pub. Year
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1 32673148 Dynamics and allostery of Zika virus non-structural protein 5 methyltransferase. 2021 Sep 1
2 32649863 Anionic Lipids Impact RAS-Binding Site Accessibility and Membrane Binding Affinity of CRAF RBD-CRD. 2020 Aug 4 1
3 33145412 GTP-State-Selective Cyclic Peptide Ligands of K-Ras(G12D) Block Its Interaction with Raf. 2020 Oct 28 1
4 30951555 Supramolecular arrangement of the full-length Zika virus NS5. 2019 Apr 2
5 28630043 The small GTPases K-Ras, N-Ras, and H-Ras have distinct biochemical properties determined by allosteric effects. 2017 Aug 4 1
6 28783719 Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS. 2017 Aug 10 1
7 28855513 Noninvasive Imaging of Ras Activity by Monomolecular Biosensor Based on Split-Luciferase Complementary Assay. 2017 Aug 30 1
8 25775415 A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication. 2015 Mar 1
9 24696348 Construction of plasmid, bacterial expression, purification, and assay of dengue virus type 2 NS5 methyltransferase. 2014 2
10 21862573 Activation kinetics of RAF protein in the ternary complex of RAF, RAS-GTP, and kinase on the plasma membrane of living cells: single-molecule imaging analysis. 2011 Oct 21 1
11 20230813 The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activation. 2010 May 15 1
12 18458061 Electrostatic interactions positively regulate K-Ras nanocluster formation and function. 2008 Jul 2
13 16475808 Ras regulation by reactive oxygen and nitrogen species. 2006 Feb 21 2
14 16569214 Neuronal nitric oxide synthase-induced S-nitrosylation of H-Ras inhibits calcium ionophore-mediated extracellular-signal-regulated kinase activity. 2006 Jul 15 1
15 15067337 Induction of p97MAPK expression regulates collagen mediated inhibition of proliferation and migration in human squamous cell carcinoma lines. 2004 May 1
16 12446733 The requirement of specific membrane domains for Raf-1 phosphorylation and activation. 2003 Jan 31 1
17 12748287 Identification of tetratricopeptide repeat 1 as an adaptor protein that interacts with heterotrimeric G proteins and the small GTPase Ras. 2003 Jun 1
18 12801936 Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras. 2003 Aug 8 1
19 12894505 The antitumor ether lipid 1-Q-octadecyl-2-O-methyl-rac-glycerophosphocholine (ET-18-OCH3) inhibits the association between Ras and Raf-1. 2003 May-Jun 1
20 11953426 Associations of B- and C-Raf with cholesterol, phosphatidylserine, and lipid second messengers: preferential binding of Raf to artificial lipid rafts. 2002 Jul 5 1
21 11971897 Activation of c-Raf kinase by ultraviolet light. Regulation by retinoids. 2002 Jun 28 1
22 12006650 Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells. 2002 May 2
23 10712905 Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak. 2000 Mar 9 1
24 9931261 Nuclear magnetic resonance and molecular dynamics studies on the interactions of the Ras-binding domain of Raf-1 with wild-type and mutant Ras proteins. 1999 Feb 12 2
25 10234739 Fusion of the binding domain of Raf-1 kinase with green fluorescent protein for activated Ras detection by fluorescence correlation spectroscopy. 1999 Apr 1
26 10319320 16K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells. 1999 May 1
27 9525855 Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C. 1998 Apr 3 4
28 9780005 Prolonged vs transient roles for early cell cycle signaling components. 1998 Aug 20 1
29 9199317 Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway. 1997 Jul 1
30 8626511 The differential effects of the Gly-60 to Ala mutation on the interaction of H-Ras p21 with different downstream targets. 1996 Apr 5 1
31 7542586 Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation. 1995 Jul 3 1
32 7576990 p21ras: an oncoprotein functioning in growth factor-induced signal transduction. 1995 Jul-Aug 1
33 7604263 Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases. 1995 Jun 30 2
34 8607981 Interactions between Ras and Raf: key regulatory proteins in cellular transformation. 1995 Dec 1
35 7983008 Identification of discrete segments of human Raf-1 kinase critical for high affinity binding to Ha-Ras. 1994 Dec 9 1
36 8002932 The Ras-related protein R-ras interacts directly with Raf-1 in a GTP-dependent manner. 1994 Jun 1 4
37 8024815 Sequential protein kinase reactions controlling cell growth and differentiation. 1994 Apr 1
38 8349650 Kappa B site-dependent induction of gene expression by diverse inducers of nuclear factor kappa B requires Raf-1. 1993 Aug 25 1
39 8378348 GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells. 1993 Sep 15 1
40 8503013 Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase. 1993 Jun 11 2