Title : Electrostatic interactions positively regulate K-Ras nanocluster formation and function.

Pub. Date : 2008 Jul

PMID : 18458061






2 Functional Relationships(s)
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1 We show using high-resolution spatial mapping that Raf-1 is recruited to and retained in K-Ras-GTP nanoclusters. Guanosine Triphosphate Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens
2 Similarly, upon epidermal growth factor receptor activation, Raf-1 is preferentially recruited to K-Ras-GTP and not H-Ras-GTP nanoclusters. Guanosine Triphosphate Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens