Title : Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak.

Pub. Date : 2000 Mar 9

PMID : 10712905






1 Functional Relationships(s)
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1 Activation of the protein kinase Raf-1 is a complex process involving association with the GTP-bound form of Ras (Ras-GTP), membrane translocation and both serine/threonine and tyrosine phosphorylation (reviewed in [1]). Guanosine Triphosphate Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens