Pub. Date : 2006 Feb 21
PMID : 16475808
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We further demonstrate that NO/O(2) and O(2)(*)(-) promote Ras GDP exchange with GTP in the presence of a radical-quenching agent, ascorbate, or NO, and generation of Ras-GTP promotes high-affinity binding of the Ras-binding domain of Raf-1, a downstream effector of Ras. | Guanosine Triphosphate | Raf-1 proto-oncogene, serine/threonine kinase | Homo sapiens |
| 2 | We further demonstrate that NO/O(2) and O(2)(*)(-) promote Ras GDP exchange with GTP in the presence of a radical-quenching agent, ascorbate, or NO, and generation of Ras-GTP promotes high-affinity binding of the Ras-binding domain of Raf-1, a downstream effector of Ras. | Guanosine Triphosphate | Raf-1 proto-oncogene, serine/threonine kinase | Homo sapiens |