Title : The antitumor ether lipid 1-Q-octadecyl-2-O-methyl-rac-glycerophosphocholine (ET-18-OCH3) inhibits the association between Ras and Raf-1.

Pub. Date : 2003 May-Jun

PMID : 12894505






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 MATERIALS AND METHODS: The interaction of Raf-1 with Ras was examined by investigating the association of cytosolic Raf-1, from ET-18-OCH3-treated and untreated cells with purified GST-Ras-GTP-gamma-S bound to agarose beads. Guanosine Triphosphate Raf-1 proto-oncogene, serine/threonine kinase Homo sapiens