Testosterone

steroid 5 alpha-reductase 2 ; Homo sapiens







63 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 32702725 Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride. 2020 Jul 15 2
2 33110062 Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride. 2020 Oct 27 2
3 30353958 A 5α-reductase (SRD5A2) polymorphism is associated with serum testosterone and sex hormone-binding globulin in men, while aromatase (CYP19A1) polymorphisms are associated with oestradiol and luteinizing hormone reciprocally. 2019 Feb 1
4 30616540 Unbiased data mining identifies cell cycle transcripts that predict non-indolent Gleason score 7 prostate cancer. 2019 Jan 7 1
5 30703436 In silico and functional studies reveal novel loss-of-function variants of SRD5A2, but no variants explaining excess 5α-reductase activity. 2019 Jun 1
6 31272082 Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study. 2019 Aug 1 1
7 31601057 In silico screening of potential lead compounds against 3-oxo-5-alpha-steroid 4-dehydrogenase 2 for treating prostate cancer. 2019 Oct 5 1
8 32894851 Spectrum of Pathogenic Variants in SRD5A2 in Indian Children with 46,XY Disorders of Sex Development and Clinically Suspected Steroid 5α-Reductase 2 Deficiency. 2019 3
9 29610568 Longer TA repeat but not V89L polymorphisms in the SRD5A2 gene may confer acne risk in the Chinese population. 2018 Feb 2
10 27848231 Association of SRD5A2 gene mutations with risk of hypospadias in the Iranian population. 2017 Apr 2
11 28323036 Targeting androgen receptor versus targeting androgens to suppress castration resistant prostate cancer. 2017 Jul 1 1
12 28324044 Inverse Regulation of DHT Synthesis Enzymes 5α-Reductase Types 1 and 2 by the Androgen Receptor in Prostate Cancer. 2017 Apr 1 1
13 28685147 Genotyping the High Altitude Mestizo Ecuadorian Population Affected with Prostate Cancer. 2017 2
14 26857022 The prognostic impact of serum testosterone during androgen-deprivation therapy in patients with metastatic prostate cancer and the SRD5A2 polymorphism. 2016 Jun 4
15 25598933 The association of 5-alpha reductase type 2 (SRD5A2) gene polymorphisms with prostate cancer in a Korean population. 2015 Jan 2
16 25735326 SRD5A2 gene polymorphisms and the risk of benign prostatic hyperplasia but not prostate cancer. 2015 1
17 24793988 Steroidogenesis of the testis -- new genes and pathways. 2014 May 2
18 24898559 Effect of dutasteride 0.5 mg/d in men with androgenetic alopecia recalcitrant to finasteride. 2014 Nov 1
19 25310105 Polymorphism of the SRD5A2 gene and the risk of prostate cancer. 2014 Dec 1
20 25336703 Genetic variations associated with the effect of testicular cancer treatment on gonadal hormones. 2014 Dec 2
21 23505265 Sex dependent influence of a functional polymorphism in steroid 5-α-reductase type 2 (SRD5A2) on post-traumatic stress symptoms. 2013 Apr 3
22 22707254 Association of V89L SRD5A2 polymorphism with craving and serum leptin levels in male alcohol addicts. 2012 Dec 2
23 20349245 Practical approach to steroid 5alpha-reductase type 2 deficiency. 2011 Jan 1
24 21177315 Meta-analysis of three polymorphisms in the steroid-5-alpha-reductase, alpha polypeptide 2 gene (SRD5A2) and risk of prostate cancer. 2011 May 1
25 21511288 Hypospadias risk and polymorphism in SRD5A2 and CYP17 genes: case-control study among Indian children. 2011 Jun 1
26 20151762 Changes of metabolic profile in men treated for androgenetic alopecia with 1 mg finasteride. 2010 Jan 1
27 20823678 Establishment of a novel model for studying the effects of extracts of Chinese herb medicine on human type II 5alpha-reductase in vitro. 2010 Sep 1
28 19443907 Longer (TA)n repeat but not A49T and V89L polymorphisms in SRD5A2 gene may confer prostate cancer risk in South Indian men. 2009 Nov-Dec 1
29 19492581 Genetic analysis of the SRD5A2 gene in Indian patients with 5alpha-reductase deficiency. 2009 Mar 1
30 18469342 No association between the SRD5A2 gene A49T missense variant and prostate cancer risk: lessons learned. 2008 Aug 15 1
31 18483391 VDR and SRD5A2 polymorphisms combine to increase risk for prostate cancer in both non-Hispanic White and Hispanic White men. 2008 May 15 1
32 19169095 Finasteride-induced myalgia and HyperCKemia. 2008 Dec 1
33 17646096 Establishment of type II 5alpha-reductase over-expressing cell line as an inhibitor screening model. 2007 Nov-Dec 2
34 15811930 Combined inhibition of types I and II 5 alpha-reductase selectively augments the basal (nonpulsatile) mode of testosterone secretion in young men. 2005 Jul 1
35 16155734 Androgenic correlates of genetic variation in the gene encoding 5alpha-reductase type 1. 2005 1
36 16181229 SRD5A2 gene analysis in an Italian population of under-masculinized 46,XY subjects. 2005 Oct 1
37 14560315 Comprehensive evaluation of the association between prostate cancer and genotypes/haplotypes in CYP17A1, CYP3A4, and SRD5A2. 2004 Apr 1
38 14991867 Association of prostate cancer risk and aggressiveness to androgen pathway genes: SRD5A2, CYP17, and the AR. 2004 Apr 1 1
39 15064320 Compound heterozygous mutations in the SRD5A2 gene exon 4 in a male pseudohermaphrodite patient of Chinese origin. 2004 May-Jun 1
40 15194142 Role of TGF-beta2 in the human hair cycle. 2004 Jun 1
41 15326487 Identification and characterization of somatic steroid 5alpha-reductase (SRD5A2) mutations in human prostate cancer tissue. 2004 Sep 23 1
42 12712437 Polymorphic markers in the 5alpha-reductase type II gene and the incidence of prostate cancer. 2003 Jul 1 1
43 12746845 Evaluation of SRD5A2 sequence variants in susceptibility to hereditary and sporadic prostate cancer. 2003 Jun 15 1
44 12815006 Association between two polymorphisms in the SRD5A2 gene and serum androgen concentrations in British men. 2003 Jun 1
45 12843198 Micropenis and the 5alpha-reductase-2 (SRD5A2) gene: mutation and V89L polymorphism analysis in 81 Japanese patients. 2003 Jul 1
46 12949937 Decreased gene expression of steroid 5 alpha-reductase 2 in human prostate cancer: implications for finasteride therapy of prostate carcinoma. 2003 Oct 1 2
47 12042668 5alpha-reductase 2 polymorphisms as risk factors in prostate cancer. 2002 Jun 1
48 12111704 Association of polymorphisms within androgen receptor, 5alpha-reductase, and PSA genes with prostate volume, clinical parameters, and endocrine status in elderly men. 2002 Jul 1 1
49 11340572 Impact of genetic polymorphisms of 17-hydroxylase cytochrome P-450 (CYP17) and steroid 5alpha-reductase type II (SRD5A2) genes on prostate-cancer risk among the Japanese population. 2001 Jun 1 1
50 11355945 A missense substitution A49T in the steroid 5-alpha-reductase gene (SRD5A2) is not associated with prostate cancer in Finland. 2001 May 18 1