Title : Evaluation of SRD5A2 sequence variants in susceptibility to hereditary and sporadic prostate cancer.

Pub. Date : 2003 Jun 15

PMID : 12746845






1 Functional Relationships(s)
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1 BACKGROUND: The 5 alpha-reductase type II (SRD5A2) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT), and is thus believed to be the key enzyme for the control of intracellular DHT level in the prostate. Testosterone steroid 5 alpha-reductase 2 Homo sapiens