Title : Inverse Regulation of DHT Synthesis Enzymes 5α-Reductase Types 1 and 2 by the Androgen Receptor in Prostate Cancer.

Pub. Date : 2017 Apr 1

PMID : 28324044






1 Functional Relationships(s)
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1 5alpha-Reductase types 1 and 2, encoded by SRD5A1 and SRD5A2, are the two enzymes that can catalyze the conversion of testosterone to dihydrotestosterone, the most potent androgen receptor (AR) agonist in prostate cells. Testosterone steroid 5 alpha-reductase 2 Homo sapiens