Title : Role of TGF-beta2 in the human hair cycle.

Pub. Date : 2004 Jun

PMID : 15194142






1 Functional Relationships(s)
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1 These lines of evidence strongly suggest the presence of a "catagen cascade" in male pattern baldness, involving: (1) the conversion of testosterone to DHT by type II 5-alpha-reductase; (2) the synthesis of TGF-beta2 in dermal papilla cells; and (3) the activation of the intrinsic caspase network. Testosterone steroid 5 alpha-reductase 2 Homo sapiens