| 1 |
35079622 | FDX2 and ISCU Gene Variations Lead to Rhabdomyolysis With Distinct Severity and Iron Regulation. | 2022 Feb |
2 |
| 2 |
34199378 | Molecular Details of the Frataxin-Scaffold Interaction during Mitochondrial Fe-S Cluster Assembly. | 2021 Jun 2 |
1 |
| 3 |
32131593 | Molecular Mechanism of ISC Iron-Sulfur Cluster Biogenesis Revealed by High-Resolution Native Mass Spectrometry. | 2020 Apr 1 |
1 |
| 4 |
32202031 | Distribution of Nitrogen-Fixation Genes in Prokaryotes Containing Alternative Nitrogenases. | 2020 Jun 15 |
1 |
| 5 |
32776106 | Assembly of the [4Fe-4S] cluster of NFU1 requires the coordinated donation of two [2Fe-2S] clusters from the scaffold proteins, ISCU2 and ISCA1. | 2020 Nov 25 |
2 |
| 6 |
30557609 | DHA inhibits proliferation and induces ferroptosis of leukemia cells through autophagy dependent degradation of ferritin. | 2019 Feb 1 |
2 |
| 7 |
30586625 | Phosphoinositide-3-kinase inhibition elevates ferritin level resulting depletion of labile iron pool and blocking of glioma cell proliferation. | 2019 Mar |
2 |
| 8 |
31101807 | Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism. | 2019 May 17 |
1 |
| 9 |
31344531 | Exploring iron-binding to human frataxin and to selected Friedreich ataxia mutants by means of NMR and EPR spectroscopies. | 2019 Nov |
1 |
| 10 |
31395877 | Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin. | 2019 Aug 8 |
5 |
| 11 |
29210568 | Comparison of the Response of Bacterial IscU and SufU to Zn2+ and Select Transition-Metal Ions. | 2018 Mar 16 |
4 |
| 12 |
29406711 | ISCU(M108I) and ISCU(D39V) Differ from Wild-Type ISCU in Their Failure To Form Cysteine Desulfurase Complexes Containing Both Frataxin and Ferredoxin. | 2018 Mar 6 |
3 |
| 13 |
29572489 | Iron regulatory protein deficiency compromises mitochondrial function in murine embryonic fibroblasts. | 2018 Mar 23 |
2 |
| 14 |
29576242 | Interactions of iron-bound frataxin with ISCU and ferredoxin on the cysteine desulfurase complex leading to Fe-S cluster assembly. | 2018 Jun |
2 |
| 15 |
29596470 | Dysfunction in the mitochondrial Fe-S assembly machinery leads to formation of the chemoresistant truncated VDAC1 isoform without HIF-1α activation. | 2018 |
1 |
| 16 |
29689452 | Role of the HSPA9/HSC20 chaperone pair in promoting directional human iron-sulfur cluster exchange involving monothiol glutaredoxin 5. | 2018 Jul |
2 |
| 17 |
29782976 | LdIscU is a [2Fe-2S] scaffold protein which interacts with LdIscS and its expression is modulated by Fe-S proteins in Leishmania donovani. | 2018 Sep |
1 |
| 18 |
29802141 | A missed Fe-S cluster handoff causes a metabolic shakeup. | 2018 May 25 |
1 |
| 19 |
29983374 | Architectural Features of Human Mitochondrial Cysteine Desulfurase Complexes from Crosslinking Mass Spectrometry and Small-Angle X-Ray Scattering. | 2018 Aug 7 |
1 |
| 20 |
30031876 | Zinc(II) binding on human wild-type ISCU and Met140 variants modulates NFS1 desulfurase activity. | 2018 Sep |
3 |
| 21 |
30209894 | PTBP1 acts as a dominant repressor of the aberrant tissue-specific splicing of ISCU in hereditary myopathy with lactic acidosis. | 2018 Nov |
1 |
| 22 |
28001042 | Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron-Sulfur Cluster Biosynthesis. | 2017 Jan 24 |
1 |
| 23 |
28271877 | The N-Terminus of Iron-Sulfur Cluster Assembly Factor ISD11 Is Crucial for Subcellular Targeting and Interaction with l-Cysteine Desulfurase NFS1. | 2017 Mar 28 |
1 |
| 24 |
28380382 | A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III. | 2017 Apr 4 |
1 |
| 25 |
28664160 | New Techniques for Ancient Proteins: Direct Coupling Analysis Applied on Proteins Involved in Iron Sulfur Cluster Biogenesis. | 2017 |
1 |
| 26 |
28882199 | Defining the Architecture of the Core Machinery for the Assembly of Fe-S Clusters in Human Mitochondria. | 2017 |
4 |
| 27 |
26749241 | Disease-Causing SDHAF1 Mutations Impair Transfer of Fe-S Clusters to SDHB. | 2016 Feb 9 |
1 |
| 28 |
27519411 | Architecture of the Human Mitochondrial Iron-Sulfur Cluster Assembly Machinery. | 2016 Sep 30 |
1 |
| 29 |
27590019 | Glutathione-complexed [2Fe-2S] clusters function in Fe-S cluster storage and trafficking. | 2016 Oct |
1 |
| 30 |
27653419 | Real-Time Kinetic Probes Support Monothiol Glutaredoxins As Intermediate Carriers in Fe-S Cluster Biosynthetic Pathways. | 2016 Nov 18 |
1 |
| 31 |
27714045 | Mammalian Fe-S proteins: definition of a consensus motif recognized by the co-chaperone HSC20. | 2016 Oct 1 |
3 |
| 32 |
27783661 | The High Level of Aberrant Splicing of ISCU in Slow-Twitch Muscle May Involve the Splicing Factor SRSF3. | 2016 |
2 |
| 33 |
25447544 | Anatomy of an iron-sulfur cluster scaffold protein: Understanding the determinants of [2Fe-2S] cluster stability on IscU. | 2015 Jun |
1 |
| 34 |
25597503 | Mammalian frataxin directly enhances sulfur transfer of NFS1 persulfide to both ISCU and free thiols. | 2015 Jan 19 |
1 |
| 35 |
26032732 | Interaction of frataxin, an iron binding protein, with IscU of Fe-S clusters biogenesis pathway and its upregulation in AmpB resistant Leishmania donovani. | 2015 Aug |
2 |
| 36 |
26342079 | Mapping Key Residues of ISD11 Critical for NFS1-ISD11 Subcomplex Stability: IMPLICATIONS IN THE DEVELOPMENT OF MITOCHONDRIAL DISORDER, COXPD19. | 2015 Oct 23 |
2 |
| 37 |
26560363 | Regulation of iron homeostasis by the p53-ISCU pathway. | 2015 Nov 12 |
7 |
| 38 |
24111776 | HypoxamiRs and cancer: from biology to targeted therapy. | 2014 Sep 10 |
1 |
| 39 |
24281368 | Deleterious mutation in FDX1L gene is associated with a novel mitochondrial muscle myopathy. | 2014 Jul |
1 |
| 40 |
24498631 | Exome sequencing identifies NFS1 deficiency in a novel Fe-S cluster disease, infantile mitochondrial complex II/III deficiency. | 2014 Jan |
3 |
| 41 |
24573684 | The presence of multiple cellular defects associated with a novel G50E iron-sulfur cluster scaffold protein (ISCU) mutation leads to development of mitochondrial myopathy. | 2014 Apr 11 |
2 |
| 42 |
24606901 | Cochaperone binding to LYR motifs confers specificity of iron sulfur cluster delivery. | 2014 Mar 4 |
2 |
| 43 |
24917298 | The role of zinc in the stability of the marginally stable IscU scaffold protein. | 2014 Sep |
1 |
| 44 |
24976419 | Mammalian target of rapamycin coordinates iron metabolism with iron-sulfur cluster assembly enzyme and tristetraprolin. | 2014 Sep |
1 |
| 45 |
25044349 | The scaffold protein IscU retains a structured conformation in the Fe-S cluster assembly complex. | 2014 Jul 21 |
2 |
| 46 |
23137639 | Iron-sulfur cluster scaffold (ISCU) gene is duplicated in salmonid fish and tissue and temperature dependent expressed in rainbow trout. | 2013 Jan 10 |
4 |
| 47 |
23265191 | Mammalian frataxin controls sulfur production and iron entry during de novo Fe4S4 cluster assembly. | 2013 Jan 16 |
2 |
| 48 |
23508953 | Mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation stabilizes ISCU protein: implications for iron metabolism. | 2013 May 3 |
4 |
| 49 |
23586717 | Characterization of iron-sulfur cluster assembly protein IscA from Acidithiobacillus ferrooxidans. | 2013 Mar |
3 |
| 50 |
23796308 | Thermodynamic and structural analysis of human NFU conformational chemistry. | 2013 Jul 23 |
2 |