Pub. Date : 2018 Mar 16
PMID : 29210568
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | IscU, the central scaffold protein in the bacterial ISC iron-sulfur (Fe-S) cluster biosynthesis system, has long been recognized to bind a Zn2+ ion at its active site. | Iron | iron-sulfur cluster assembly enzyme | Homo sapiens |
| 2 | While initially regarded as an artifact, Zn2+ binding has been shown to induce stabilization of the IscU structure that may mimic a state biologically relevant to IscU"s role in Fe-S cluster biosynthesis. | Iron | iron-sulfur cluster assembly enzyme | Homo sapiens |
| 3 | While initially regarded as an artifact, Zn2+ binding has been shown to induce stabilization of the IscU structure that may mimic a state biologically relevant to IscU"s role in Fe-S cluster biosynthesis. | Iron | iron-sulfur cluster assembly enzyme | Homo sapiens |
| 4 | Monitoring and comparing the conformational behavior and stabilization afforded by different transition metal ions upon IscU and SufU revealed similarities between the two proteins and suggest that metal-dependent conformational transitions may be characteristic of U-type proteins involved in Fe-S cluster biosynthesis. | Iron | iron-sulfur cluster assembly enzyme | Homo sapiens |