Pub. Date : 2018 Mar 23
PMID : 29572489
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we report that Irp1 or Irp2-null mutation also causes downregulation of frataxin and IscU, two of the core components in the iron-sulfur cluster biogenesis machinery. | Iron | iron-sulfur cluster assembly enzyme | Homo sapiens |
| 2 | Overexpression of human ISCU and frataxin in Irp1 or Irp2-null cells was able to rescue the defects in iron-sulfur cluster biogenesis and mitochondrial quality. | Iron | iron-sulfur cluster assembly enzyme | Homo sapiens |