Title : Deciphering antihormone-induced compensatory mechanisms in breast cancer and their therapeutic implications.

Pub. Date : 2006 Dec

PMID : 17259561






1 Functional Relationships(s)
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1 Based on our promising studies selectively inhibiting EGFR (gefitinib), NFkappaB (parthenolide) or CD59 (neutralising antibody) together with antioestrogens, we propose that co-targeting strategies could markedly improve anti-tumour activity (notably enhancing cell kill) during the antihormone-responsive phase. parthenolide nuclear factor kappa B subunit 1 Homo sapiens