Tyrosine

tyrosyl-DNA phosphodiesterase 1 ; Homo sapiens







18 Article(s)
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1 34181949 Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus. 2021 Aug 1
2 34768766 New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1. 2021 Oct 20 2
3 32152270 TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts. 2020 Mar 9 1
4 29856574 [Tyrosyl-DNA phosphodiesterases: potential targets for cancer treatment]. 2016 Feb 1
5 26121557 A Theoretical Study of Phosphoryl Transfers of Tyrosyl-DNA Phosphodiesterase I (Tdp1) and the Possibility of a "Dead-End" Phosphohistidine Intermediate. 2015 Jul 14 1
6 23688965 A fluorescence-based assay for the apurinic/apyrimidinic-site cleavage activity of human tyrosyl-DNA phosphodiesterase 1. 2013 Sep 1 2
7 22522093 Tyrosyl-DNA phosphodiesterase 1 initiates repair of apurinic/apyrimidinic sites. 2012 Aug 2
8 21463258 Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1. 2011 Jun 15 1
9 19139134 Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assay. 2009 Jan 1
10 15647511 Deficiency in 3'-phosphoglycolate processing in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1). 2005 1
11 15811850 Substrate specificity of tyrosyl-DNA phosphodiesterase I (Tdp1). 2005 Jun 10 1
12 14761185 Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes. 2004 Feb 12 2
13 15111055 Analysis of human tyrosyl-DNA phosphodiesterase I catalytic residues. 2004 May 14 1
14 15333697 Design and synthesis of fluorescent substrates for human tyrosyl-DNA phosphodiesterase I. 2004 1
15 12618186 Crystal structure of a transition state mimic for Tdp1 assembled from vanadate, DNA, and a topoisomerase I-derived peptide. 2003 Feb 2
16 11839309 The crystal structure of human tyrosyl-DNA phosphodiesterase, Tdp1. 2002 Feb 1
17 12023295 Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1. 2002 Jul 26 1
18 12470949 Insights into substrate binding and catalytic mechanism of human tyrosyl-DNA phosphodiesterase (Tdp1) from vanadate and tungstate-inhibited structures. 2002 Dec 13 1