Title : Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assay.

Pub. Date : 2009 Jan

PMID : 19139134






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Tdp1 catalyzes the hydrolysis of the phosphodiester bond between the catalytic tyrosine residue of topoisomerase I and the DNA 3"-phosphate. Tyrosine tyrosyl-DNA phosphodiesterase 1 Homo sapiens