Title : A Theoretical Study of Phosphoryl Transfers of Tyrosyl-DNA Phosphodiesterase I (Tdp1) and the Possibility of a "Dead-End" Phosphohistidine Intermediate.

Pub. Date : 2015 Jul 14

PMID : 26121557






1 Functional Relationships(s)
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Protein Name
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1 Tyrosyl-DNA phosphodiesterase I (Tdp1) is a DNA repair enzyme conserved across eukaryotes that catalyzes the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3"-phosphate of DNA. Tyrosine tyrosyl-DNA phosphodiesterase 1 Homo sapiens